Autologous hematopoietic stem cell transplantation (aHSCT) is a well-established treatment
for malignancies such as multiple myeloma (MM) and lymphomas. Various changes in the …

Categorizing prognostic variables is essential for their use in clinical decision‐making. Often
a single cutpoint that stratifies patients into high‐risk and low‐risk categories is sought …

Chimeric antigen receptor (CAR) T-cell therapy targeting CD19 may be associated with long-
term adverse effects such as cytopenia and immune deficiency. In order to characterize …

The host tissue microenvironment influences malignant cell proliferation and metastasis, but
little is known about how tumor-induced changes in the microenvironment affect benign …

Stromal cell-derived factor 1 (SDF1/CXCL12) and its cognate receptor, CXCR4, play key
regulatory roles in CD34+ cell trafficking. We investigated whether AMD3100, a selective …

Background In recipients of allogeneic hematopoietic-cell transplants, peripheral-blood cells
mobilized with the use of filgrastim (recombinant granulocyte colony-stimulating factor) …

Background Bone marrow contains stem cells with the potential to differentiate into mature
cells of various organs. We determined whether circulating stem cells have a similar …

As more efficient agents for stem cell mobilization are being developed, there is an urgent
need to define which patient population might benefit from these novel drugs. For a precise …

To test the hypothesis that aging has negative effects on stem-cell homing and engraftment,
young or old C57BL/6 bone marrow (BM) cells were injected, using a limiting-dilution …

PURPOSE: To review recent advances in peripheral-blood progenitor-cell (PBPC)
transplantation in order to define the optimal cell dose required for autologous and …