Living Leukocyte‐Based Drug Delivery Systems
Leukocytes play a vital role in immune responses, including defending against invasive
pathogens, reconstructing impaired tissue, and maintaining immune homeostasis. When the …
pathogens, reconstructing impaired tissue, and maintaining immune homeostasis. When the …
[HTML][HTML] Biomimetic platelet membrane-coated nanoparticles for targeted therapy
H Han, R Bartolo, J Li, MA Shahbazi… - European Journal of …, 2022 - Elsevier
The development of cell membrane-modified biomimetic nanoparticles has extensively
increased during the past years due to their exceptional biocompatibility, evasion from the …
increased during the past years due to their exceptional biocompatibility, evasion from the …
Sensitive activatable nanoprobes for real‐time ratiometric magnetic resonance imaging of reactive oxygen species and ameliorating inflammation in vivo
X Li, Y Liu, X Qi, S Xiao, Z Xu, Z Yuan, Q Liu… - Advanced …, 2022 - Wiley Online Library
Imaging‐guided real‐time monitoring of the treatment process of inflammatory diseases is
important for the timely adjustment of treatment planning to lower unnecessary side effects …
important for the timely adjustment of treatment planning to lower unnecessary side effects …
Accelerating thrombolysis using a precision and clot-penetrating drug delivery strategy by nanoparticle-shelled microbubbles
Conventional thrombolytic drugs for vascular blockage such as tissue plasminogen activator
(tPA) are challenged by the low bioavailability, off-target side effects and limited penetration …
(tPA) are challenged by the low bioavailability, off-target side effects and limited penetration …
Biomimetic nanoparticles carrying a repolarization agent of tumor-associated macrophages for remodeling of the inflammatory microenvironment following …
Y Yue, F Li, Y Li, Y Wang, X Guo, Z Cheng, N Li, X Ma… - ACS …, 2021 - ACS Publications
The complete regression of residual tumors after photothermal therapy (PTT) depends on
the activation and recognition of the immune system. However, the inevitable local …
the activation and recognition of the immune system. However, the inevitable local …
Drug targeting via platelet membrane–coated nanoparticles
Platelets exhibit distinct surface moieties responsible for modulating their adhesion to
various disease‐relevant substrates involving vascular damage, immune evasion, and …
various disease‐relevant substrates involving vascular damage, immune evasion, and …
An inhalable hybrid biomimetic nanoplatform for sequential drug release and remodeling lung immune homeostasis in acute lung injury treatment
Interactions of lung macrophages and recruited neutrophils with the lung microenvironment
continuously aggravate the dysregulation of lung inflammation in the pathogenesis of acute …
continuously aggravate the dysregulation of lung inflammation in the pathogenesis of acute …
Biomimetic cell membrane‐coated poly(lactic‐co‐glycolic acid) nanoparticles for biomedical applications
N Jan, A Madni, S Khan, H Shah… - Bioengineering & …, 2023 - Wiley Online Library
Poly (lactic‐co‐glycolic acid)(PLGA) nanoparticles (NPs) are commonly used for drug
delivery because of their favored biocompatibility and suitability for sustained and controlled …
delivery because of their favored biocompatibility and suitability for sustained and controlled …
Penetrating macrophage-based nanoformulation for periodontitis treatment
Periodontitis is a chronic inflammatory disease caused by the interaction of oral
microorganisms with the host immune response. Porphyromonas gingivalis (Pg) acts as a …
microorganisms with the host immune response. Porphyromonas gingivalis (Pg) acts as a …
Rescuing ischemic stroke by biomimetic nanovesicles through accelerated thrombolysis and sequential ischemia-reperfusion protection
W Yu, N Yin, Y Yang, C Xuan, X Liu, W Liu, Z Zhang… - Acta biomaterialia, 2022 - Elsevier
Rational design of nanomedicine to accelerate thrombolysis and sequentially avoid
thrombolysis-mediated reperfusion injury is still a challenge. Here, we develop a biomimetic …
thrombolysis-mediated reperfusion injury is still a challenge. Here, we develop a biomimetic …