The creation of skin substitutes has significantly decreased morbidity and mortality of skin
wounds. Although there are still a number of disadvantages of currently available skin …

Background An ulcer is a trophic lesion with loss of tissue that often has a multifactorial
genesis. It typically diverges from the physiologic processes of regeneration because it …

Healing in wounds like pressure ulcers, diabetic ulcers, venous ulcers, and arterial
insufficiency ulcers is immensely hampered and causes both an economic burden and …

Infection control is necessary for improved burn wound regeneration. In this study contact
burn wounds were induced on the dorsum of the rats and were infected with Pseudomonas …

Many cell-based regenerative medicine strategies toward tissue-engineered constructs are
currently being explored. Cell–cell interactions and interactions with different biomaterials …

Generation of reactive oxygen species (ROS) by NADPH oxidase 4 (Nox4) induces the
proliferation and migration of adipose‐derived stem cells (ASCs). However, the functional …

Even though the stem cells have been studied for decades, only during the past few years
has there been an overwhelming proliferation of publications covering isolation, cultivation …

Skin substitutes are epidermal, dermal or complete bilayered constructs, composed by
natural or synthetic scaffolds and by adherent cells such as fibroblasts, keratinocytes or …

Although artificial dermis (AD) is effective for skin reconstruction, it requires two separate
procedures, because the AD must be vascularised before skin grafts. To shorten the period …

Adipose-derived stromal cells (ASCs) are mostly isolated by enzymatic digestion,
centrifugation and adherent growth resulting in a very heterogeneous cell population …