[HTML][HTML] UVA-triggered drug release and photo-protection of skin

VW Karisma, W Wu, M Lei, H Liu, MF Nisar… - Frontiers in Cell and …, 2021 - frontiersin.org
Light has attracted special attention as a stimulus for triggered drug delivery systems (DDS)
due to its intrinsic features of being spatially and temporally tunable. Ultraviolet A (UVA) …

Various biological effects of solar radiation on skin and their mechanisms: implications for phototherapy

DW Shin - Animal cells and systems, 2020 - Taylor & Francis
The skin protects our body from various external factors, such as chemical and physical
stimuli, microorganisms, and sunlight. Sunlight is a representative environmental factor that …

Biocompatible light guide‐assisted wearable devices for enhanced UV light delivery in deep skin

H Zhang, H Zhao, X Zhao, C Xu… - Advanced Functional …, 2021 - Wiley Online Library
Phototherapy represents an attractive route for treating a range of challenging
dermatological diseases. Existing skin phototherapy modalities rely on direct UV …

Tryptophan photo-product FICZ upregulates AHR/MEK/ERK-mediated MMP1 expression: Implications in anti-fibrotic phototherapy

M Murai, K Yamamura, A Hashimoto-Hachiya… - Journal of …, 2018 - Elsevier
Background Scleroderma is caused by aberrant transforming growth factor-ß signaling. The
degradation of extracellular matrix proteins is regulated by matrix metalloproteinases …

UV increases skin-derived 1α, 25-dihydroxyvitamin D3 production, leading to MMP-1 expression by altering the balance of vitamin D and cholesterol synthesis from 7 …

MH Shin, Y Lee, MK Kim, DH Lee, JH Chung - The Journal of Steroid …, 2019 - Elsevier
The skin is a unique site in the human body that has the capacity to synthesize the active
form of vitamin D, 1α, 25-dihydroxyvitamin D 3 (1α, 25 (OH) 2 D 3), from 7 …

Morphea patients with mucocutaneous involvement: A cross-sectional study from the Morphea in Adults and Children (MAC) cohort

S Prasad, SM Black, JL Zhu, S Sharma… - Journal of the American …, 2021 - Elsevier
Background Demographic and clinical findings of patients with mucocutaneous morphea
have not been well characterized, to our knowledge. Objective To determine the …

Deciphering the Effects of Different Types of Sunlight Radiation on Skin Function: A Review

S Letsiou, E Koldiri, A Beloukas, E Rallis, V Kefala - Cosmetics, 2024 - mdpi.com
Sunlight radiation is a fundamental component of our daily lives. Specifically, blue light as
well as UV light appear to play a role in the development of oxidative stress, DNA damage …

[PDF][PDF] Morphea–Selected local treatment methods and their effectiveness

J Narbutt, A Hołdrowicz, A Lesiak - Reumatologia/Rheumatology, 2017 - termedia.pl
Localised scleroderma is an uncommon connective tissue disease of multifactorial aetiology
occurring in the paediatric and adult population. It is relatively difficult to conduct any …

Effectiveness of PUVA vs. UVA1 phototherapy in the treatment of morphea patients

A Malewska-Woźniak, A Osmola-Mañkowska… - … in Dermatology and …, 2022 - termedia.pl
Results The study shows that patients in both groups experienced improvement based on
clinical measures, resulting in a reduction in the clinical score in all groups. There is positive …

EuroGuiderm guideline on lichen sclerosus—Treatment of lichen sclerosus

G Kirtschig, M Kinberger, A Kreuter… - Journal of the …, 2024 - Wiley Online Library
Introduction Lichen sclerosus (LS) is an inflammatory skin disease affecting all ages. LS
typically involves the anogenital site where it causes itching and soreness; it may lead to …