Biomarkers of conversion to α-synucleinopathy in isolated rapid-eye-movement sleep behaviour disorder

MG Miglis, CH Adler, E Antelmi, D Arnaldi… - The Lancet …, 2021 - thelancet.com
Patients with isolated rapid-eye-movement sleep behaviour disorder (RBD) are commonly
regarded as being in the early stages of a progressive neurodegenerative disease involving …

[HTML][HTML] Predictors of RBD progression and conversion to synucleinopathies

ER de Natale, H Wilson, M Politis - Current Neurology and Neuroscience …, 2022 - Springer
Purpose of review Rapid eye movement (REM) sleep behaviour disorder (RBD) is
considered the expression of the initial neurodegenerative process underlying …

Possible predictors of phenoconversion in isolated REM sleep behaviour disorder: a systematic review and meta-analysis

C Wang, F Chen, Y Li, J Liu - Journal of Neurology, Neurosurgery & …, 2022 - jnnp.bmj.com
Background A number of promising biomarkers for predicting imminent α-synucleinopathies
have been suggested in isolated rapid eye movement sleep behaviour disorder (iRBD) …

Considering REM sleep behavior disorder in the management of Parkinson's disease

M Figorilli, M Meloni, G Lanza, E Casaglia… - Nature and Science …, 2023 - Taylor & Francis
Rapid eye movement (REM) sleep behavior disorder (RBD) is the result of the loss of
physiological inhibition of muscle tone during REM sleep, characterized by dream-enacting …

Prodromal dementia with Lewy bodies in REM sleep behavior disorder: A multicenter study

S Joza, MT Hu, KY Jung, D Kunz… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION Isolated/idiopathic rapid eye movement sleep behavior disorder (iRBD) is
a powerful early predictor of dementia with Lewy bodies (DLB) and Parkinson's disease …

[HTML][HTML] Predictive risk factors of phenoconversion in idiopathic REM sleep behavior disorder: the Italian study “FARPRESTO”

M Puligheddu, M Figorilli, E Antelmi, D Arnaldi… - Neurological …, 2022 - Springer
Most patients with idiopathic REM sleep behavior disorder (iRBD) will develop an overt α-
synucleinopathy over time, with a rate of phenoconversion of 73.5% after 12 years from …

Severity of REM sleep without atonia correlates with measures of cognitive impairment and depressive symptoms in REM sleep behaviour disorder

M Figorilli, F Meloni, R Lecca… - Journal of Sleep …, 2023 - Wiley Online Library
This study aimed to correlate REM sleep without atonia (RSWA) and neuropsychological
data in patients with idiopathic/isolated REM sleep behaviour disorder (iRBD) and those …

Neuropsychological changes in isolated rem sleep behavior disorder: a systematic review and meta-analysis of cross-sectional and longitudinal studies

C Leitner, G D'Este, L Verga, S Rahayel… - Neuropsychology …, 2024 - Springer
The aim of this meta-analysis is twofold:(a) to assess cognitive impairments in isolated rapid
eye movement (REM) sleep behavior disorder (iRBD) patients compared to healthy controls …

Neuropsychiatric, neuropsychological, and neuroimaging features in isolated REM sleep behavior disorder: the importance of MCI

M Vacca, F Assogna, C Pellicano, A Chiaravalloti… - Sleep Medicine, 2022 - Elsevier
Background Mild cognitive impairment (MCI) is frequently diagnosed in patients with
isolated rapid eye movement (REM) sleep behavior disorder (iRBD), although the extent of …

Influence of RBD onset on the clinical characteristics of Parkinson's disease patients: a retrospective study

CE Cicero, A Luca, G Mostile, G Donzuso… - Journal of …, 2023 - Springer
Abstract Introduction In Parkinson's disease (PD), rapid eye movement (REM) sleep
behavior disorder (RBD) might either precede the appearance of motor symptoms, or …