[HTML][HTML] Therapeutic strategies aimed at improving neuroplasticity in Alzheimer disease

MF Colavitta, FJ Barrantes - Pharmaceutics, 2023 - mdpi.com
Alzheimer disease (AD) is the most prevalent form of dementia among elderly people.
Owing to its varied and multicausal etiopathology, intervention strategies have been highly …

[HTML][HTML] The impact of hormesis, neuronal stress response, and reproduction, upon clinical aging: a narrative review

M Kyriazis, L Swas, T Orlova - Journal of Clinical Medicine, 2023 - mdpi.com
Introduction: The primary objective of researchers in the biology of aging is to gain a
comprehensive understanding of the aging process while developing practical solutions that …

[HTML][HTML] The systemic effects of the enriched environment on the conditioned fear reaction

GA Grigoryan - Frontiers in Behavioral Neuroscience, 2023 - frontiersin.org
In this review, a hypothesis is proposed to explain the beneficial effect of an enriched
environment (EE) on the conditioned fear reaction (CFR) from the perspective of a functional …

[HTML][HTML] Improved connectivity and cognition due to cognitive stimulation in Alzheimer's disease

Q Behfar, N Richter, M Kural, A Clemens… - Frontiers in aging …, 2023 - frontiersin.org
Background Due to the increasing prevalence of Alzheimer's disease (AD) and the limited
efficacy of pharmacological treatment, the interest in non-pharmacological interventions, eg …

Involvement of Glucosamine 6 Phosphate Isomerase 2 (GNPDA2) Overproduction in β-Amyloid-and Tau P301L-Driven Pathomechanisms

M Lachén-Montes, P Cartas-Cejudo, A Cortés… - Biomolecules, 2024 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative olfactory disorder affecting millions of
people worldwide. Alterations in the hexosamine-or glucose-related pathways have been …

[HTML][HTML] Hypometabolism, alzheimer's disease, and possible therapeutic targets: an overview

S Raut, A Bhalerao, M Powers, M Gonzalez… - Cells, 2023 - mdpi.com
The brain is a highly dynamic organ that requires a constant energy source to function
normally. This energy is mostly supplied by glucose, a simple sugar that serves as the …