Aging is a gradual and irreversible pathophysiological process. It presents with declines in
tissue and cell functions and significant increases in the risks of various aging-related …

Non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH) has become the leading
cause of liver disease worldwide. NASH, an advanced form of NAFL, can be progressive …

With changing lifestyles, non-alcoholic fatty liver disease (NAFLD) has become the most
prevalent liver disease worldwide. A substantial increase in the incidence, mortality, and …

Despite the increase in the global prevalence of metabolic dysfunction-associated fatty liver
disease (MAFLD), no approved drug currently exists for the disease. Poria cocos (Schw.) …

Chronic liver diseases affect over a billion people worldwide and often lead to fibrosis.
Nonalcoholic steatohepatitis (NASH), a disease paralleling a worldwide surge in metabolic …

Disturbance of the gut microbiota plays a critical role in the development of nonalcoholic
fatty liver disease (NAFLD). Increasing evidence supports that natural products may serve as …

Hepatic fibrosis (HF) refers to the pathophysiological process of connective tissue dysplasia
in the liver caused by various pathogenic factors. Nowadays, HF is becoming a severe threat …

Hepatocellular carcinoma (HCC, accounting for 90% of primary liver cancer) was the sixth
most common cancer in the world and the third leading cause of cancer death in 2020. The …

Globally, tens of millions of individuals experience osteoarthritis (OA), a degenerative joint
condition for which a definitive cure is currently lacking. This condition is characterized by …

Scutellarin related drugs have superior therapeutic effects on cerebrovascular and
cardiovascular diseases. Here, an optimal biosynthetic pathway for scutellarin was …