Novel anti-inflammatory approaches to COPD

M Cazzola, NA Hanania, CP Page… - International journal of …, 2023 - Taylor & Francis
Airway inflammation, driven by different types of inflammatory cells and mediators, plays a
fundamental role in COPD and its progression. Neutrophils, eosinophils, macrophages, and …

Rational use of inhaled corticosteroids for the treatment of COPD

JK Quint, A Ariel, PJ Barnes - npj Primary Care Respiratory Medicine, 2023 - nature.com
Inhaled corticosteroids (ICS) are the mainstay of treatment for asthma, but their role in
chronic obstructive pulmonary disease (COPD) is debated. Recent randomised controlled …

Inhaled Corticosteroids in Subjects with Chronic Obstructive Pulmonary Disease: An Old, Unfinished History

AS Melani, S Croce, G Fabbri, M Messina, E Bargagli - Biomolecules, 2024 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is one of the major causes of disability and
death. Maintenance use of inhaled bronchodilator (s) is the cornerstone of COPD …

Asthma and post-asthmatic fibrosis: a search for new promising molecular markers of transition from acute inflammation to pulmonary fibrosis

IA Savin, AV Markov, MA Zenkova, AV Sen'kova - Biomedicines, 2022 - mdpi.com
Asthma is a heterogeneous pulmonary disorder, the progression and chronization of which
leads to airway remodeling and fibrogenesis. To understand the molecular mechanisms of …

Blood and Sputum Eosinophils of COPD Patients Are Differently Polarized than in Asthma

K Mycroft, M Paplińska-Goryca, M Proboszcz… - Cells, 2023 - mdpi.com
Different eosinophil subpopulations have been identified in asthma and other eosinophilic
disorders. However, there is a paucity of data on eosinophil subpopulations in patients with …

[HTML][HTML] Urban-rural and socio-economic differences in inhaled corticosteroid treatment for chronic obstructive pulmonary disease: a nationwide register-based cross …

A Klitgaard, R Ibsen, O Hilberg, A Løkke - Respiratory Medicine, 2024 - Elsevier
Background Urban-rural disparities within chronic obstructive pulmonary disease (COPD)
have been documented in USA, but not in Europe. Inhaled corticosteroids (ICS) are widely …

ICS/Ultra LABA in the Treatment of Obstructive Airway Diseases: A Consensus of Indian Experts

R Dhar, D Talwar, P James, A Mishra… - … in Respiratory Medicine, 2022 - mdpi.com
Highlights What are the main findings? FF/Vi is an effective choice for patients who are
uncontrolled on their current Asthma treatment and also for controlled Asthma patients …

Overuse of long-acting β2-agonist/inhaled corticosteroids in patients with chronic obstructive pulmonary disease: time to rethink prescribing patterns

SA Brunton, DK Hogarth - Postgraduate Medicine, 2023 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity
and mortality globally. In the major revision of the Global Initiative for Chronic Obstructive …

A qualitative study on asthma management experiences of Turkish community pharmacists

E Ulutas Deniz, AN Gülakar, R Eren - Journal of Asthma, 2024 - Taylor & Francis
Introduction Asthma is seen in more than 4 million people in Turkey. Numerous studies have
shown the beneficial effects of pharmacist interventions on medication adherence and …

[HTML][HTML] Journal Club: Biologics and Potential for Immune Modulation in Chronic Obstructive Lung Disease

T Mkorombindo, R Balkissoon - Chronic Obstructive Pulmonary …, 2022 - ncbi.nlm.nih.gov
This chronic inflammatory change and repetitive injury from tobacco smoke and other
exposures propagate a cascade of events, including airway remodeling, that results in fixed …