EvgS/EvgA, the unorthodox two-component system regulating bacterial multiple resistance

R Zhang, Y Wang - Applied and Environmental Microbiology, 2023 - Am Soc Microbiol
Two-component systems (TCSs) widely exist in bacteria and assist bacteria in adjusting
behaviors to adapt to environmental changes after sensing environmental signals and …

FN1 and cancer‐associated fibroblasts markers influence immune microenvironment in clear cell renal cell carcinoma

G Ashok, S Ramaiah - The Journal of Gene Medicine, 2023 - Wiley Online Library
Background Altered tumor microenvironment (TME) is characterized in clear cell renal cell
carcinoma (ccRCC) as a result of the heterogeneity observed in the TME. Modulations in …

[HTML][HTML] Translational protein RpsE as an alternative target for novel nucleoside analogues to treat MDR Enterobacter cloacae ATCC 13047: network analysis and …

R Debroy, S Ramaiah - World Journal of Microbiology and Biotechnology, 2023 - Springer
The pathogenic Enterobacter cloacae subsp. cloacae str. ATCC 13047 has contemporarily
emerged as a multi-drug resistant strain. To formulate an effective treatment option …

Pan-genome and reverse vaccinology approaches to design multi-epitope vaccine against Epstein-Barr virus associated with colorectal cancer

P Priyamvada, S Ramaiah - Immunologic Research, 2023 - Springer
Epstein-Barr virus (EBV) is a global lymphotropic virus and has been associated with
various malignancies, among which colorectal cancer (CRC) is the prevalent one causing …

A hypothetical model of multi-layered cost-effective wastewater treatment plant integrating microbial fuel cell and nanofiltration technology: a comprehensive review on …

A Naha, S Antony, S Nath, D Sharma, A Mishra… - Environmental …, 2023 - Elsevier
Wastewater management has emerged as an uprising concern that demands immediate
attention from environmentalists worldwide. Indiscriminate and irrational release of industrial …

Potential signature therapeutic biomarkers TOP2A, MAD2L1, and CDK1 in colorectal cancer: a systems biomedicine-based approach

P Priyamvada, S Ramaiah - Biochemical Genetics, 2023 - Springer
Colorectal cancer is the third deadliest and fourth most diagnosed cancer. It is
heterogeneously driven by varied mutations and mutagens, and thus, it is challenging for …

Structure Elucidation and Interaction Dynamics of MefA-MsrD Efflux Proteins in Streptococcus pneumoniae: Impact on Macrolide Susceptibility

SCM Peela, S Basu, J Sharma, AF AlAsmari… - ACS …, 2023 - ACS Publications
Macrolides are empirically used to treat bacterial community-acquired pneumonia (CAP).
Streptococcus pneumoniae, being the major pathogen responsible for bacterial CAP with …

Comprehensive analysis on the diagnostic role of circulatory exosome‐based miR‐92a‐3p for osteoblastic metastases in prostate adenocarcinoma

G Ashok, R Das, A Anbarasu… - Journal of Molecular …, 2023 - Wiley Online Library
Prostate adenocarcinoma (PRAD) is the second leading cause of death in men and the key
factor that attributes to the severity and higher mortality rates is the tumor's ability to promote …

Novel Antimicrobial Peptide SAAP Mutant as a Better Adjuvant to Sulbactam-Based Treatments Against Clinical Strains of XDR Acinetobacter baumannii

A Naha, S Ramaiah - Probiotics and Antimicrobial Proteins, 2024 - Springer
The production of extended spectrum β-lactamases (ESBLs) in extensively drug-resistant
(XDR) strains of Acinetobacter baumannii has created havoc amongst clinicians making the …

Consolidated knowledge-guided computational pipeline for therapeutic intervention against bacterial biofilms-a review

R Debroy, S Ramaiah - Biofouling, 2023 - Taylor & Francis
Biofilm-associated bacterial infections attributed to multifactorial antimicrobial resistance
have caused worldwide challenges in formulating successful treatment strategies. In search …