Abstract Background. Nonneutralizing antibodies (Abs) involved in antibody-dependent
cellular cytotoxicity (ADCC) may provide some protection from influenza virus infection. The …

This study aims to provide comparative data on clinical features and in-hospital outcomes
among US adults admitted to the hospital with COVID-19 and influenza infection using a …

Interferons have prominent roles in various pathophysiological conditions, mostly related to
inflammation. Interferon-gamma (IFNγ) was, initially discovered as a potent antiviral agent …

Influenza A virus (IAV) is a major global public health burden due to its routine evasion of
immunization strategies. Natural killer (NK) cells are innate cytotoxic cells with important …

Pregnant women experience increased morbidity and mortality after influenza infection, for
reasons that are not understood. Although some data suggest that natural killer (NK)-and T …

Background Innate immunity, armed with pattern recognition receptors including Toll-like
receptors (TLR), is critical for immune cell activation and the connection to anti-microbial …

Influenza vaccines elicit antigen-specific antibodies and immune memory to protect humans
from infection with drift variants. However, what supports or limits vaccine efficacy and …

There is an urgent need for innovative therapies against ovarian cancer, one of the leading
causes of death from gynecological cancers in the United States. Immunotherapy employing …

A number of studies have investigated the potential on-specific effects of some routinely
administered vaccines (eg, influenza, pneumococcal) on COVID-19 related outcomes, with …

Studies to develop cell-based therapies for cancer and other diseases have consistently
shown that purified human natural killer (NK) cells secrete cytokines and kill target cells after …