Collagens serve essential mechanical functions throughout the body, particularly in the
connective tissues. In articular cartilage, collagens provide most of the biomechanical …

The development of molecular biomarkers for disease makes it possible for preventative
medicine approaches to be considered. Therefore, therapeutics, treatments, or clinical …

Over the past three decades, many methods have been developed to evaluate levels of
biomarkers in autoimmune diseases. Early investigations have shown that some biomarkers …

Abstract Chemokine receptor 7 (CCR7) is a G protein-coupled receptor containing 7
transmembrane domains that is expressed on various cells, such as naive T/B cells, central …

Background Ferroptosis, an iron-dependent manner of lipid peroxidative cell death, has
recently been reported to be strongly associated with rheumatoid arthritis (RA). Targeted …

Background Bone metabolism can maintain the normal homeostasis and function of bone
tissue. Once the bone metabolism balance is broken, it will cause osteoporosis …

This study explored the role of the long non-coding RNA (lncRNA) XIST (X-inactive specific
transcript) as a driver of RA pathogenesis, with a particular focus on the ability of this lncRNA …

Rheumatoid arthritis (RA) is a chronic, progressive, inflammatory, autoimmune disease that
could be disabling throughout its course. It affects people in their most reproductive years …

Ferroptosis is a recently discovered cell programmed death. Extensive researches have
indicated that ferroptosis plays an essential role in tumorigenesis, development, migration …

Rheumatoid arthritis (RA) is a chronic debilitating autoimmune disease, that causes joint
damage, deformities, and decreased functionality. In addition, RA can also impact organs …