[HTML][HTML] Integrins in wound healing, fibrosis and tumor stroma: High potential targets for therapeutics and drug delivery
Wound healing is a complex process, which ultimately leads to fibrosis if not repaired well.
Pathologically very similar to fibrosis is the tumor stroma, found in several solid tumors which …
Pathologically very similar to fibrosis is the tumor stroma, found in several solid tumors which …
Alcohol abuse, alcoholism, and damage to the immune system—a review
RT Cook - Alcoholism: Clinical and Experimental Research, 1998 - Wiley Online Library
Chronic alcohol abuse exacts a major social and medical toll in the United States and other
Western countries. One of the least appreciated medical complications of alcohol abuse is …
Western countries. One of the least appreciated medical complications of alcohol abuse is …
Consequences of alcohol consumption on host defence
G Szabo - Alcohol and alcoholism, 1999 - academic.oup.com
This communication reviews recent literature and summarizes current views on the
immunomodulatory effects of acute and chronic alcohol consumption. Chronic and even …
immunomodulatory effects of acute and chronic alcohol consumption. Chronic and even …
[PDF][PDF] Chronic alcohol intoxication induces hepatic injury through enhanced macrophage inflammatory protein‐2 production and intercellular adhesion molecule‐1 …
AP Bautista - Hepatology, 1997 - Wiley Online Library
This study tested the hypothesis that prolonged consumption of alcohol directly or indirectly,
through endotoxin influx in the circulation, stimulates the Kupffer cells to produce …
through endotoxin influx in the circulation, stimulates the Kupffer cells to produce …
Neutrophilic infiltration in alcoholic hepatitis
AP Bautista - Alcohol, 2002 - Elsevier
Leukocyte infiltration in the liver is one of the most important features of alcoholic liver
disease. However, in alcoholic hepatitis, the role of polymorphonuclear neutrophils (PMNs) …
disease. However, in alcoholic hepatitis, the role of polymorphonuclear neutrophils (PMNs) …
Role of integrins in fibrosing liver diseases
E Patsenker, F Stickel - American journal of physiology …, 2011 - journals.physiology.org
Integrins and other cell adhesion molecules regulate numerous physiological and
pathological mechanisms by mediating the interaction between cells and their extracellular …
pathological mechanisms by mediating the interaction between cells and their extracellular …
Laboratory models available to study alcohol‐induced organ damage and immune variations: choosing the appropriate model
NB D'Souza El‐Guindy, EJ Kovacs… - Alcoholism: clinical …, 2010 - Wiley Online Library
The morbidity and mortality resulting from alcohol‐related diseases globally impose a
substantive cost to society. To minimize the financial burden on society and improve the …
substantive cost to society. To minimize the financial burden on society and improve the …
Ethanol‐induced liver injury: potential roles for egr‐1
MT Pritchard, LE Nagy - Alcoholism: Clinical and Experimental …, 2005 - Wiley Online Library
Chronic ethanol‐induced liver injury follows a typical progression from its earliest stage of
steatosis to more advanced injury, characterized by the development of inflammation …
steatosis to more advanced injury, characterized by the development of inflammation …
Alcohol binge before trauma/hemorrhage impairs integrity of host defense mechanisms during recovery
P Greiffenstein, KW Mathis, CV Stouwe… - Alcoholism: Clinical …, 2007 - Wiley Online Library
Background: Alcohol abuse, both chronic and acute, is a known modulator of immune
function and is associated with increased incidence of traumatic injury. Previously, we …
function and is associated with increased incidence of traumatic injury. Previously, we …