Curcumin and its derivatives in cancer therapy: Potentiating antitumor activity of cisplatin and reducing side effects
AJ Abadi, S Mirzaei, MK Mahabady… - Phytotherapy …, 2022 - Wiley Online Library
Curcumin is a phytochemical isolated from Curcuma longa with potent tumor‐suppressor
activity, which has shown significant efficacy in pre‐clinical and clinical studies. Curcumin …
activity, which has shown significant efficacy in pre‐clinical and clinical studies. Curcumin …
Cancer cachexia: definition, staging, and emerging treatments
J Ni, L Zhang - Cancer management and research, 2020 - Taylor & Francis
Cachexia is a multifactorial disease characterized by weight loss via skeletal muscle and
adipose tissue loss, an imbalance in metabolic regulation, and reduced food intake. It is …
adipose tissue loss, an imbalance in metabolic regulation, and reduced food intake. It is …
[HTML][HTML] Understanding cachexia as a cancer metabolism syndrome
PE Porporato - Oncogenesis, 2016 - nature.com
Metabolic reprogramming occurs in tumors to foster cancer cell proliferation, survival and
metastasis, but as well at a systemic level affecting the whole organism, eventually leading …
metastasis, but as well at a systemic level affecting the whole organism, eventually leading …
Sarcopenic obesity and myosteatosis are associated with higher mortality in patients with cirrhosis
AJ Montano‐Loza, P Angulo… - Journal of cachexia …, 2016 - Wiley Online Library
Background and aims Obesity is frequently associated with cirrhosis, and cirrhotic patients
may develop simultaneous loss of skeletal muscle and gain of adipose tissue, culminating in …
may develop simultaneous loss of skeletal muscle and gain of adipose tissue, culminating in …
TNF-α and cancer cachexia: Molecular insights and clinical implications
HJ Patel, BM Patel - Life sciences, 2017 - Elsevier
Cancer cachexia characterized by a chronic wasting syndrome, involves skeletal muscle
loss and adipose tissue loss and resistance to conventional nutritional support. Cachexia is …
loss and adipose tissue loss and resistance to conventional nutritional support. Cachexia is …
[HTML][HTML] Cancer cachexia, mechanism and treatment
T Aoyagi, KP Terracina, A Raza… - World journal of …, 2015 - ncbi.nlm.nih.gov
It is estimated that half of all patients with cancer eventually develop a syndrome of
cachexia, with anorexia and a progressive loss of adipose tissue and skeletal muscle mass …
cachexia, with anorexia and a progressive loss of adipose tissue and skeletal muscle mass …
[HTML][HTML] Pancreatic cancer and cachexia—metabolic mechanisms and novel insights
KA Poulia, P Sarantis, D Antoniadou, E Koustas… - Nutrients, 2020 - mdpi.com
Cachexia is a major characteristic of multiple non-malignant diseases, advanced and
metastatic cancers and it is highly prevalent in pancreatic cancer, affecting almost 70%–80 …
metastatic cancers and it is highly prevalent in pancreatic cancer, affecting almost 70%–80 …
[HTML][HTML] From sarcopenia to frailty: a road less traveled
The physical frailty phenotype consists of fatigue, weight loss, and loss of muscle power.
Sarcopenia has been shown to be a major cause of frailty. Six societies including SCWD …
Sarcopenia has been shown to be a major cause of frailty. Six societies including SCWD …
[HTML][HTML] Impact of physical exercise in cancer survivors during and after antineoplastic treatments
M Ferioli, G Zauli, AM Martelli, M Vitale, JA McCubrey… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Cancer patients experience symptoms and adverse effects of treatments that may last even
after the end of treatments. Exercise is a safe, non-pharmacological and cost-effective …
after the end of treatments. Exercise is a safe, non-pharmacological and cost-effective …
[HTML][HTML] Inflammation based regulation of cancer cachexia
JK Onesti, DC Guttridge - BioMed research international, 2014 - ncbi.nlm.nih.gov
Cancer cachexia, consisting of significant skeletal muscle wasting independent of nutritional
intake, is a major concern for patients with solid tumors that affects surgical, therapeutic, and …
intake, is a major concern for patients with solid tumors that affects surgical, therapeutic, and …