CCDC (coiled-coil domain-containing) is a coiled helix domain that exists in natural proteins.
There are about 180 CCDC family genes, encoding proteins that are involved in intercellular …

Pediatric brain tumors comprise a diverse set of diseases.(Epi) genomic analyses have
provided insights into the biology of these tumors, stratifying them into distinct subtypes with …

Diffuse gliomas in adults encompass a heterogenous group of central nervous system
neoplasms. In recent years, extensive (epi-) genomic profiling has identified several glioma …

Pediatric brain and spinal cancers are collectively the leading disease-related cause of
death in children; thus, we urgently need curative therapeutic strategies for these tumors. To …

Leptomeningeal disease (LMD) in pediatric brain tumors (PBTs) is a poorly understood and
categorized phenomenon. LMD incidence rates, as well as diagnosis, treatment, and …

Choroid plexus tumors (CPTs) are intraventricular tumors derived from the choroid plexus
epithelium and occur frequently in children. The aim of this study was to investigate the …

Choroid plexus tumors (CPT) are rare and highly vascularized neoplasms that have three
histologically confirmed diagnoses, including choroid plexus papilloma, atypical choroid …

Abstract Background Choroid plexus carcinomas (CPCs) are rare aggressive pediatric
tumors of the brain with no treatment standards. Genetic profiling of CPCs is often confined …

Infant brain tumours are rare and heterogenous, with overall poor outcomes. Advances in
molecular genetics have been incorporated into their diagnostic criteria and allow for …

Choroid plexus papilloma (CPP) is a rare, slow-growing, and typically benign brain tumor
that predominantly affects children. CPP is characterized by well-defined circular or …