Determinants of early life leptin levels and later life degenerative outcomes

DM Alexe, G Syridou, ET Petridou - Clinical medicine & research, 2006 - Marshfield Clinic
The early (intrauterine and neonatal) life environment plays an important role in
programming the susceptibility in later life to chronic degenerative diseases, such as …

The impact of diet during early life and its contribution to later disease: critical checkpoints in development and their long-term consequences for metabolic health …

ME Symonds, SP Sebert, H Budge - Proceedings of the Nutrition …, 2009 - cambridge.org
Changes in maternal diet at different stages of reproduction can have pronounced
influences on the health and well-being of the resulting offspring, especially following …

Umbilical cord leptin predicts neonatal bone mass

MK Javaid, KM Godfrey, P Taylor, SM Robinson… - Calcified Tissue …, 2005 - Springer
Evidence is accumulating that the risk of osteoporosis in later life may be determined in part
by environmental influences on bone development during intrauterine and early postnatal …

Different indices of fetal growth predict bone size and volumetric density at 4 years of age

NC Harvey, PA Mahon, SM Robinson… - Journal of Bone and …, 2010 - academic.oup.com
We have demonstrated previously that higher birth weight is associated with greater peak
and later‐life bone mineral content and that maternal body build, diet, and lifestyle influence …

Effect of maternal asthma, inhaled glucocorticoids and cigarette use during pregnancy on the newborn insulin-like growth factor axis

VL Clifton, NA Hodyl, VE Murphy, WB Giles… - Growth Hormone & IGF …, 2010 - Elsevier
BACKGROUND: Fetal growth varies in a sex-specific manner in response to maternal
asthma during pregnancy, but the mechanisms are unclear. OBJECTIVE: We examined the …

Spatial and developmental regulation of leptin in fetal sheep

RA Ehrhardt, AW Bell… - American Journal of …, 2002 - journals.physiology.org
To better understand the biology of leptin during prenatal life, the developmental and spatial
regulation of leptin was studied in ovine fetuses. Fetal plasma leptin increased steadily …

Maternal treatment with dexamethasone at minimal therapeutic doses inhibits neonatal bone development in a gender-dependent manner

E Tomaszewska, P Dobrowolski, A Siwicki - Livestock science, 2012 - Elsevier
The structural quality of bone is genetically determined, and remains under the influence of
hormonal modification. A gender-dependent effect of prenatal treatment with multiple …

Influence of birth-related maternal and neonatal factors on the levels of energy metabolism mediators in infants born at 32 or fewer weeks of gestation

A Petrova, R Mehta - The Journal of Maternal-Fetal & Neonatal …, 2023 - Taylor & Francis
Background Energy metabolism mediators, which include the adipokines (leptin,
adiponectin, ghrelin) and insulin-like growth factor 1 [IGF-1], are hormone-like proteins …

The effect of umbilical venous constriction on placental development, cord length and perinatal outcome

SM Skulstad, S Rasmussen, S Seglem… - Early human …, 2005 - Elsevier
BACKGROUND: Umbilical vein constriction at the fetal abdominal inlet is a common finding
after week 13, when the period of umbilical herniation is brought to an end. AIMS: To test the …

[PDF][PDF] Maternal glucocorticoid treatment as a model for examining foetal gender-specific effects on the bone metabolism of neonatal piglets

E Tomaszewska, P Dobrowolski - Journal of Veterinary Research, 2012 - sciendo.com
The aim of the study was to investigate gender-specific effects of a maternal treatment with
dexamethasone (DEX) at multiple maximum therapeutic doses during the last 25 d of …