Metabolic syndrome (MetS) and thyroid dysfunction are common in clinical practice. The
objectives of this review are to discuss some proposed mechanisms by which thyroid …

Alzheimer's disease (AD) and Type 2 Diabetes Mellitus (T2DM) are two of the most
prevalent diseases in the elderly population worldwide. A growing body of epidemiological …

Regulatory T (T reg) cells are garnering increased attention in research related to
autoimmune diseases, including rheumatoid arthritis (RA). They play an essential role in the …

Aim Considering the clinical efficacy of dapagliflozin in patients with type 2 DM and the
pathophysiological relevance of Kv channels for vascular reactivity. We investigate the …

Calcium (Ca2+) can regulate a wide variety of cellular fates, such as proliferation, apoptosis,
and autophagy. More importantly, changes in the intracellular Ca2+ level can modulate …

The role of thyroid hormones (THs) in the cardiovascular (CV) system, through several direct
and indirect effects is recognized. Even very small modification in TH levels (as those …

Hypothyroidism is a common endocrine disorder that predominantly occurs in females. It is
associated with an increased risk of cardiovascular diseases (CVD), but the molecular …

Sixty palmatine (PMT) derivatives were synthesized and evaluated for antiplatelet
aggregation taking berberine as the lead, and the structure–activity relationship was first …

Atherosclerosis is the onset of endothelial cell damage and is characterized by abnormal
accumulation of fibrinogen and lipid in large and middle arteries. Recent researches …

Nitric oxide (NO) produced in the wall of blood vessels is necessary for the regulation of
vascular tone to ensure an adequate blood supply of organs and tissues. In this review, we …