Advanced bioluminescence system for in vivo imaging with brighter and red-shifted light emission

M Endo, T Ozawa - International Journal of Molecular Sciences, 2020 - mdpi.com
In vivo bioluminescence imaging (BLI), which is based on luminescence emitted by the
luciferase–luciferin reaction, has enabled continuous monitoring of various biochemical …

Engineering with NanoLuc: a playground for the development of bioluminescent protein switches and sensors

L Biewenga, BJHM Rosier… - Biochemical Society …, 2020 - portlandpress.com
The small engineered luciferase NanoLuc has rapidly become a powerful tool in the fields of
biochemistry, chemical biology, and cell biology due to its exceptional brightness and …

Cell uptake and tissue distribution of radioiodine labelled D-luciferin: implications for luciferase based gene imaging

KH Lee, SS Byun, JY Paik, SY Lee… - Nuclear medicine …, 2003 - journals.lww.com
Optical luciferase gene imaging is emerging as a method to monitor gene expression in
small animals. However, there is concern over how regional availability of exogenously …

Bioluminescent imaging systems for assay developments

SB Kim, R Paulmurugan - Analytical Sciences, 2021 - jstage.jst.go.jp
Bioluminescence (BL) is an excellent optical readout platform that has great potential to be
utilized in various bioassays and molecular imaging. The advantages of BL-based …

Ratiometric bioluminescent indicator for a simple and rapid measurement of thrombin activity using a smartphone

M Hattori, N Sugiura, T Wazawa, T Matsuda… - Analytical …, 2021 - ACS Publications
Hemostasis is an essential function that repairs tissues and maintains the survival of living
organisms. To prevent diseases caused by the abnormality of the blood coagulation …

Identification of insulin-mimetic plant extracts: from an in vitro high-content screen to blood glucose reduction in live animals

V Stadlbauer, C Neuhauser, T Aumiller, A Stallinger… - Molecules, 2021 - mdpi.com
Type 2 diabetes mellitus (T2DM) is linked to insulin resistance and a loss of insulin
sensitivity, leading to millions of deaths worldwide each year. T2DM is caused by reduced …

Fluorescence microscopy-based quantitation of GLUT4 translocation: high throughput or high content?

V Stadlbauer, P Lanzerstorfer, C Neuhauser… - International journal of …, 2020 - mdpi.com
Due to the global rise of type 2 diabetes mellitus (T2DM) in combination with insulin
resistance, novel compounds to efficiently treat this pandemic disease are needed …

Protein-Nucleic Acid Conjugation Based on Hedgehog Protein Autoprocessing: Method Development and Biosensing Applications

X Zhang - 2021 - search.proquest.com
Protein-nucleic acid conjugates combine the various functionality of proteins with the
sequence-directing property of nucleic acids, enabling a variety of powerful biomedical …