Role of long non-coding RNAs in pancreatic cancer pathogenesis and treatment resistance-A review

TM Al-Noshokaty, A Mansour, R Abdelhamid… - … -Research and Practice, 2023 - Elsevier
Pancreatic cancer (PC) is one of the deadliest cancers associated with poor prognosis. The
lack of reliable means of early cancer detection contributes to this disease's dismal …

Emerging roles of long noncoding RNAs in chemoresistance of pancreatic cancer

W Xie, M Chu, G Song, Z Zuo, Z Han, C Chen… - Seminars in cancer …, 2022 - Elsevier
Pancreatic cancer is one of the most common causes of cancer death in the world due to the
lack of early symptoms, metastasis occurrence and chemoresistance. Therefore, early …

[HTML][HTML] CircRNAs in anticancer drug resistance: recent advances and future potential

T Xu, M Wang, L Jiang, L Ma, L Wan, Q Chen, C Wei… - Molecular cancer, 2020 - Springer
CircRNAs are a novel class of RNA molecules with a unique closed continuous loop
structure. CircRNAs are abundant in eukaryotic cells, have unique stability and tissue …

LncRNA MEG3 suppresses PI3K/AKT/mTOR signalling pathway to enhance autophagy and inhibit inflammation in TNF-α-treated keratinocytes and psoriatic mice

ZL Tang, K Zhang, SC Lv, GW Xu, JF Zhang, HY Jia - Cytokine, 2021 - Elsevier
Background Psoriasis is a common chronic inflammatory skin disorder that causes patches
of thick red skin and silvery scales and affects 1–3% of the population, which reduces …

[HTML][HTML] Exosomal long non-coding RNAs in lung diseases

C Poulet, MS Njock, C Moermans, E Louis… - International journal of …, 2020 - mdpi.com
Within the non-coding genome landscape, long non-coding RNAs (lncRNAs) and their
secretion within exosomes are a window that could further explain the regulation, the …

LncRNA LINC00470 promotes the degradation of PTEN mRNA to facilitate malignant behavior in gastric cancer cells

J Yan, X Huang, X Zhang, Z Chen, C Ye… - Biochemical and …, 2020 - Elsevier
Gastric cancer (GC) is the fourth most frequent malignancy worldwide. Recently, long
noncoding RNA (lncRNA) LINC00470 has been demonstrated to play an oncogenic role in …

LncRNA signature in colorectal cancer

S Ghafouri-Fard, BM Hussen, A Gharebaghi… - … -Research and Practice, 2021 - Elsevier
Colorectal cancer (CRC) is among the most frequent cancers and is associated with high
mortality particularly when being diagnosed in advanced stages. Although several …

[HTML][HTML] Emerging role of long non-coding RNAs in endothelial dysfunction and their molecular mechanisms

R Jayasuriya, K Ganesan, B Xu… - Biomedicine & …, 2022 - Elsevier
Long non-coding RNAs (lncRNAs) are the novel class of transcripts involved in
transcriptional, post-transcriptional, translational, and post-translational regulation of …

[HTML][HTML] Unraveling immune-related lncRNAs in breast cancer molecular subtypes

C Mathias, JCD Muzzi, BB Antunes, DF Gradia… - Frontiers in …, 2021 - frontiersin.org
Breast cancer (BRCA) is the most leading cause of cancer worldwide. It is a heterogeneous
disease with at least five molecular subtypes including luminal A, luminal B, basal-like …

[HTML][HTML] Recent advances and future perspectives in the therapeutics of prostate cancer

GL Varaprasad, VK Gupta, K Prasad, E Kim… - … Hematology & Oncology, 2023 - Springer
Prostate cancer (PC) is one of the most common cancers in males and the fifth leading
reason of death. Age, ethnicity, family history, and genetic defects are major factors that …