A myriad of physiological processes in mammals are influenced by estrogens and the
estrogen receptors (ERs), ERα and ERβ. As we reviewed previously, given the widespread …

Colorectal cancer (CRC) is a leading cause of death in the United States. Despite its slow
development and the capacity for early diagnosis, current preventive approaches are not …

Although incidence of colorectal cancer (CRC) in the United States has declined in recent
years, rates remain higher in men than in women and the male‐to‐female incidence rate …

To review the influence of sex hormones on the progression of breast, prostate, gynecologic,
and colorectal cancer. The literature was reviewed in an informal manner utilizing the …

There are clear gender-dependent differences in response rates and the probability of side
effects in patients treated with chemotherapy. Sex-biased expression levels of metabolic …

Several studies suggest estrogen to be protective against the development of colon cancer.
Estrogen receptor β (ERβ) is the predominant estrogen receptor expressed in colorectal …

The small non-coding RNA miR-34a is a p53-regulated miRNA that acts as a tumour
suppressor of colorectal cancer (CRC). Oncogenesis is also negatively influenced by …

This is the very first book to deal with sex and gender differences in drug therapy-an
increasingly recognized medical need. It starts with an overview on S/G in clinical …

Colon cancer is a common cause of cancer death in the Western world. Accumulating
evidence supports a protective role of estrogen via estrogen receptor beta (ERβ) but the …

AIM To assess factors associated with the higher effect of metformin on mortality in diabetic
colorectal cancer (CRC) patients, since the factors related to the effectiveness of metformin …