Exosomes are nanovesicles with a wide range of chemical compositions used in many
different applications. Mesenchymal stem cell-derived exosomes (MSCs-EXOs) are …

Cellular therapy aims to replace damaged resident cells by restoring cellular and molecular
environments suitable for tissue repair and regeneration. Among several candidates …

Rationale: Ischemia/reperfusion injury (IRI) is a major cause of acute kidney injury (AKI) that
is associated with high morbidity and mortality, and for which specific treatments are lacking …

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are the severe lung
damage and respiratory failure without effective therapy. However, there was a lack of …

Gene therapy has great potential in treating neurodegenerative diseases with complex
pathologies. The combination of small interfering RNAs (siRNAs) targeting β-site amyloid …

Kidney diseases pose a threat to human health due to their rising incidence and fatality rate.
In preclinical and clinical studies, it has been acknowledged that mesenchymal stem cells …

Multiple sclerosis (MS) is a leading cause of chronic neurological disability in young to
middle-aged adults, affecting~ 2.5 million people worldwide. Currently, most therapeutics for …

Exosome extracellular vesicles as biologic therapy for COVID‐19 are discussed for two
areas. The first involves the growing use of mesenchymal stromal cells (MSCs) for the …

Donor shortage is a major problem that limits liver transplantation availability. Steatotic
donor liver presents a feasible strategy to solve this problem. However, severe ischemia …

Kidney disease (KD) is a life-threatening disease characterized by high morbidity and
mortality in clinical settings, which can be caused by many reasons, and the incidence …