Interferon gamma-treated keratinocytes activate T cells in the presence of superantigens: involvement of major histocompatibility complex class II molecules
P Strange, L Skov, O Baadsgaard - Journal of investigative dermatology, 1994 - Elsevier
During inflammation in the skin keratinocytes can express major histocompatibility complex
class II molecules but are unable to present nominal antigens to resting T cells. Certain …
class II molecules but are unable to present nominal antigens to resting T cells. Certain …
A bacterially expressed single-chain Fv construct from the 2B4 T-cell receptor.
I Kurucz, CR Jost, AJ George… - Proceedings of the …, 1993 - National Acad Sciences
A single-chain Fv construct of the 2B4 T-cell receptor has been made and expressed in
Escherichia coli as bacterial inclusion bodies. After solubilization in 6 M guanidine …
Escherichia coli as bacterial inclusion bodies. After solubilization in 6 M guanidine …
Localization of a site on bacterial superantigens that determines T cell receptor beta chain specificity.
JA Mollick, RL McMasters, D Grossman… - The Journal of …, 1993 - rupress.org
A defining characteristic of superantigens is their ability to stimulate T cells based
predominantly on the type of variable segment of the T cell receptor (TCR) beta chain (V …
predominantly on the type of variable segment of the T cell receptor (TCR) beta chain (V …
In vivo effects of superantigens
MA Blackman, DL Woodland - Life sciences, 1995 - Elsevier
Superantigens are potent immunostimulatory molecules that activate both T cells and
antigen presenting cells. The consequences of superantigen exposure range from induction …
antigen presenting cells. The consequences of superantigen exposure range from induction …
Immunopharmacology of the superantigen staphylococcal enterotoxin A in T-cell receptor V beta 3 transgenic mice.
M Dohlsten, M Björklund, A Sundstedt, G Hedlund… - …, 1993 - ncbi.nlm.nih.gov
The response of mouse T cells to the superantigen staphylococcal enterotoxin A (SEA)
requires 1000-fold higher concentrations compared to human T cells. In order to develop a …
requires 1000-fold higher concentrations compared to human T cells. In order to develop a …
The Decreased Replicative Capacity of Simian Immunodeficiency Virus SIVmac239Δnef Is Manifest in Cultures of Immature Dendritic Cells and T Cells
D Messmer, R Ignatius, C Santisteban… - Journal of …, 2000 - Am Soc Microbiol
Transmission of simian immunodeficiency virus SIVmac239Δ nef (Δ nef) to macaques
results in attenuated replication of the virus in most animals and ultimately induces …
results in attenuated replication of the virus in most animals and ultimately induces …
Effects of staphylococcal enterotoxin B on rodent mast cells
J Komisar, J Rivera, A Vega, J Tseng - Infection and immunity, 1992 - Am Soc Microbiol
Staphylococcal enterotoxin B (SEB) was tested in rodent mast cell cultures for the release of
serotonin. Both rat RBL-2H3 mast cells and murine peritoneal cells released serotonin after …
serotonin. Both rat RBL-2H3 mast cells and murine peritoneal cells released serotonin after …
Pathogenesis of parodontitis in rheumatic diseases
J Detert, N Pischon, GR Burmester… - Zeitschrift für …, 2010 - Springer
Die entzündliche Parodontalerkrankung (PD) ist eine weltweit verbreitete Krankheit, die in
erster Linie bakterieller Genese ist und durch Dysregulation der entzündlichen …
erster Linie bakterieller Genese ist und durch Dysregulation der entzündlichen …
Cutting edge: trimolecular interaction of TCR with MHC class II and bacterial superantigen shows a similar affinity to MHC: peptide ligands
S Redpath, SM Alam, CM Lin, AM O'Rourke… - The Journal of …, 1999 - journals.aai.org
Bacterial superantigens such as Staphylococcus aureus enterotoxin A (SEA) are very potent
stimulators of T cells. They bind to the Vβ region of the TCR and to MHC class II, stimulating …
stimulators of T cells. They bind to the Vβ region of the TCR and to MHC class II, stimulating …
T-cell receptor beta-chain binding to enterotoxin superantigens.
The last few years have seen an enormous jump in our knowledge and understanding of T-
cell activation by superantigens. Clearly, a great number of infectious and parasitic …
cell activation by superantigens. Clearly, a great number of infectious and parasitic …