Background: it is now known that curcumin (Cur) has a broad range of biological properties;
however, photosensitivity, as well as low bioavailability and short half-life, have limited its …

Cancer is a complex, one of the fatal non-communicable diseases, and its treatment has
enormous challenges, with variable efficacy of traditional anti-cancer agents. By 2025, it is …

With the aim of preparing hybrid hydrogels suitable for use as patches for the local treatment
of squamous cell carcinoma (SCC)-affected areas, curcumin (CUR) was loaded onto …

Retinal degeneration is the major and principal cause behind many incurable blindness
diseases. Several studies indicated the neuroprotective effect of Curcuma longa in eye …

Purpose Due to the shortcomings of nanocarriers, the development of carrier-free
nanodelivery systems has attracted more and more attention in cancer treatment. However …

Background: Various anticancer drugs are effective therapeutic agents for cancer treatment;
however, they cause severe toxicity in body organs. Cardiotoxicity is one of the most critical …

Designing optimal (neo) adjuvant therapy is a crucial aspect of the treatment of non-small-
cell lung carcinoma (NSCLC). Standard methods of chemotherapy, radiotherapy, and …

A new curcuminoid molecule (3) has been designed and synthesized, containing a central-
(CH2) 2-COOH chain at the α carbon of the keto-enol moiety in the structure. The carboxylic …

Spinal cord injury (SCI) is a serious central nervous system disease. Traumatic SCI often
causes persistent neurological deficits below the injury level. Epigenetic changes occur after …

The novel 9-cinnamyl-9 H-purine skeleton, inspired by resveratrol and curcumin, was
developed to avoid a pan-assay interference compound (PAINS) related to invalid metabolic …