Venous thromboembolism (VTE) is the third most common cardiovascular disorder, affecting
up to 5% of the population. VTE commonly manifests as lower-extremity deep venous …

Background The American College of Chest Physicians Clinical Practice Guideline on the
Perioperative Management of Antithrombotic Therapy addresses 43 Patients-Interventions …

Background Lupus anticoagulants (LA) are one laboratory criterion for classification of
antiphospholipid syndrome, with presence of vascular thrombosis and/or pregnancy/fetal …

Background In case of bleeding patients and in acute care, the assessment of residual direct
oral anticoagulant (DOAC) activity is essential for evaluating the potential impact on …

For more than a decade, US laboratories have failed to implement solutions to help their
clinicians in managing complex situations or patients on direct oral anticoagulants (DOACs) …

In certain clinical situations, it is necessary to determine whether clinically relevant plasma
levels of direct oral anticoagulants (DOACs) are present. We examined whether qualitative …

Heparin remains a critical therapy in hospitalized patients requiring anticoagulation.
Unfractionated heparin (UFH) mediates its therapeutic effect by binding to antithrombin (AT) …

abstract The class of new oral anticoagulants (NOACs) has been developed to provide
reliable oral anticoagulation without the need for therapeutic drug monitoring. Based on …

Background With the widespread use of direct oral anticoagulants (DOACs), there is an
urgent need for a rapid assay to exclude clinically relevant plasma levels. Accurate and …

The assessment of hemostasis is necessary to make suitable decisions on the management
of patients with thrombotic disorders. In some clinical situations, for example, during …