Advances in mesenchymal stem cell exosomes: a review

Y Tang, Y Zhou, HJ Li - Stem cell research & therapy, 2021 - Springer
Stem cells can be used for regenerative medicine and as treatments for disease. The
application of tissue engineering-related transplantation, stem cells, and local changes in …

Native and bioengineered extracellular vesicles for cardiovascular therapeutics

RC de Abreu, H Fernandes… - Nature reviews …, 2020 - nature.com
Extracellular vesicles (EVs) are a heterogeneous group of natural particles that are relevant
to the treatment of cardiovascular diseases. These endogenous vesicles have certain …

Human umbilical cord blood–derived MSCs exosome attenuate myocardial injury by inhibiting ferroptosis in acute myocardial infarction mice

Y Song, B Wang, X Zhu, J Hu, J Sun, J Xuan… - Cell Biology and …, 2021 - Springer
The exosome of MSCs derived from human umbilical cord blood (HUCB-MSC) has been
reported to have cardioprotective effects on mouse models of acute myocardial infarction …

Microneedle patch loaded with exosomes containing microRNA‐29b prevents cardiac fibrosis after myocardial infarction

J Yuan, H Yang, C Liu, L Shao, H Zhang… - Advanced …, 2023 - Wiley Online Library
Myocardial infarction (MI) is a cardiovascular disease that poses a serious threat to human
health. Uncontrolled and excessive cardiac fibrosis after MI has been recognized as a …

Mesenchymal stem cell-derived magnetic extracellular nanovesicles for targeting and treatment of ischemic stroke

HY Kim, TJ Kim, L Kang, YJ Kim, MK Kang, J Kim… - Biomaterials, 2020 - Elsevier
Exosomes and extracellular nanovesicles (NV) derived from mesenchymal stem cells (MSC)
may be used for the treatment of ischemic stroke owing to their multifaceted therapeutic …

Exosomes derived from human adipose mensenchymal stem cells accelerates cutaneous wound healing via optimizing the characteristics of fibroblasts

LI Hu, J Wang, X Zhou, Z Xiong, J Zhao, R Yu… - Scientific reports, 2016 - nature.com
Prolonged healing and scar formation are two major challenges in the treatment of soft
tissue trauma. Adipose mesenchymal stem cells (ASCs) play an important role in tissue …

Paracrine mechanisms of mesenchymal stromal cells in angiogenesis

S Maacha, H Sidahmed, S Jacob… - Stem cells …, 2020 - Wiley Online Library
The role of the mesenchymal stromal cell‐(MSC‐) derived secretome is becoming
increasingly intriguing from a clinical perspective due to its ability to stimulate endogenous …

The microRNA regulatory landscape of MSC-derived exosomes: a systems view

SW Ferguson, J Wang, CJ Lee, M Liu… - Scientific reports, 2018 - nature.com
Mesenchymal stem cell (MSC)-derived exosomes mediate tissue regeneration in a variety of
diseases including ischemic heart injury, liver fibrosis, and cerebrovascular disease. Despite …

Mesenchymal stem/stromal cell-derived extracellular vesicles and their potential as novel immunomodulatory therapeutic agents

V Börger, M Bremer, R Ferrer-Tur, L Gockeln… - International journal of …, 2017 - mdpi.com
Extracellular vesicles (EVs), such as exosomes and microvesicles, have been identified as
mediators of a newly-discovered intercellular communication system. They are essential …

Human umbilical cord mesenchymal stem cells derived-exosomes in diseases treatment

Y Yaghoubi, AA Movassaghpour, M Zamani, M Talebi… - Life sciences, 2019 - Elsevier
Exosomes are extracellular vesicles with the size of 40–100 nm in diameter and a density of
1.13–1.19 g/mL, containing proteins, mRNAs, miRNAs, and DNAs. Exosomes change the …