Staphylococcal enterotoxins
Staphylococcus aureus is a major human pathogen that produces a wide array of toxins,
thus causing various types of disease symptoms. Staphylococcal enterotoxins (SEs), a …
thus causing various types of disease symptoms. Staphylococcal enterotoxins (SEs), a …
Staphylococcal superantigens: pyrogenic toxins induce toxic shock
T Krakauer - Toxins, 2019 - mdpi.com
Staphylococcal enterotoxin B (SEB) and related superantigenic toxins produced by
Staphylococcus aureus are potent activators of the immune system. These protein toxins …
Staphylococcus aureus are potent activators of the immune system. These protein toxins …
Staphylococcus aureus: the toxic presence of a pathogen extraordinaire
EA Larkin, RJ Carman, T Krakauer… - Current medicinal …, 2009 - ingentaconnect.com
Staphylococcus aureus is a facultative, Gram-positive coccus well known for its disease-
causing capabilities. In particular, methicillin and vancomycin resistant strains of S. aureus …
causing capabilities. In particular, methicillin and vancomycin resistant strains of S. aureus …
Bacterial Superantigens Promote Acute Nasopharyngeal Infection by Streptococcus pyogenes in a Human MHC Class II-Dependent Manner
Establishing the genetic determinants of niche adaptation by microbial pathogens to specific
hosts is important for the management and control of infectious disease. Streptococcus …
hosts is important for the management and control of infectious disease. Streptococcus …
The mechanism of superantigen-mediated toxic shock: not a simple Th1 cytokine storm
L Faulkner, A Cooper, C Fantino… - The Journal of …, 2005 - journals.aai.org
The profound clinical consequences of Gram-positive toxic shock are hypothesized to stem
from excessive Th1 responses to superantigens. We used a new superantigen-sensitive …
from excessive Th1 responses to superantigens. We used a new superantigen-sensitive …
Immune response to staphylococcal superantigens
T Krakauer - Immunologic research, 1999 - Springer
Staphylococcal exotoxins, staphylococcal enterotoxins AE (SEA-SEE), and toxic shock
syndrome toxin-1 (TSST-1) are potent activators of the immune system and cause a variety …
syndrome toxin-1 (TSST-1) are potent activators of the immune system and cause a variety …
Update on staphylococcal superantigen-induced signaling pathways and therapeutic interventions
T Krakauer - Toxins, 2013 - mdpi.com
Staphylococcal enterotoxin B (SEB) and related bacterial toxins cause diseases in humans
and laboratory animals ranging from food poisoning, acute lung injury to toxic shock. These …
and laboratory animals ranging from food poisoning, acute lung injury to toxic shock. These …
Safety and immunogenicity of a parenterally administered, structure-based rationally modified recombinant staphylococcal enterotoxin B protein vaccine, STEBVax
WH Chen, MF Pasetti, RP Adhikari… - Clinical and Vaccine …, 2016 - Am Soc Microbiol
Staphylococcus aureus produces several enterotoxins and superantigens, exposure to
which can elicit profound toxic shock. A recombinant staphylococcal enterotoxin B (rSEB) …
which can elicit profound toxic shock. A recombinant staphylococcal enterotoxin B (rSEB) …
Development of engineered vaccines effective against structurally related bacterial superantigens
RG Ulrich, MA Olson, S Bavari - Vaccine, 1998 - Elsevier
Staphylococcal and streptococcal superantigens are exotoxins that may be linked to many
human pathologies involving impaired immune functions. Despite considerable sequence …
human pathologies involving impaired immune functions. Despite considerable sequence …
Inhibition of toxic shock by human monoclonal antibodies against staphylococcal enterotoxin B
EA Larkin, BG Stiles, RG Ulrich - PloS one, 2010 - journals.plos.org
Background Staphylococcus aureus is implicated in many opportunistic bacterial infections
around the world. Rising antibiotic resistance and few alternative methods of treatment are …
around the world. Rising antibiotic resistance and few alternative methods of treatment are …