The pentose phosphate pathway (PPP) is a route that can work in parallel to glycolysis in
glucose degradation in most living cells. It has a unidirectional oxidative part with glucose-6 …

Neutrophils are cells at the frontline of innate immunity that can quickly activate effector
functions to eliminate pathogens upon stimulation. However, little is known about the …

Heart failure (HF) is a progressive chronic disease that remains a primary cause of death
worldwide, affecting over 64 million patients. HF can be caused by cardiomyopathies and …

Oxidative stress modulates carcinogenesis in the liver; however, direct evidence for
metabolic control of oxidative stress during pathogenesis, particularly, of progression from …

Transaldolase deficiency predisposes to chronic liver disease progressing from cirrhosis to
hepatocellular carcinoma (HCC). Transition from cirrhosis to hepatocarcinogenesis depends …

Simple Summary The article presents the role of alpha-fetoprotein in the diagnosis and
monitoring of treatment for selected genetic diseases and early childhood cancers. The …

Erythritol is a non-nutritive sugar replacement that can be endogenously produced by
humans. Witkowski et al. reported that elevated circulating erythritol is associated with …

Mutations in the transaldolase 1 (TALDO1) gene have been described in a limited number of
cases. Several organs can be affected and clinical manifestations are variable, but often …

Macrophages are crucial effector cells of the innate immune system and have important
roles in the initiation and resolution of inflammation as well as in tissue homeostasis. To …

Kidney disease is a global health burden with high morbidity and mortality. Causes of kidney
disease are numerous, extending from common disease groups like diabetes and arterial …