Impact of sepsis on CD4 T cell immunity
J Cabrera-Perez, SA Condotta… - Journal of leukocyte …, 2014 - academic.oup.com
Sepsis remains the primary cause of death from infection in hospital patients, despite
improvements in antibiotics and intensive-care practices. Patients who survive severe sepsis …
improvements in antibiotics and intensive-care practices. Patients who survive severe sepsis …
T cells and their immunometabolism: A novel way to understanding sepsis immunopathogenesis and future therapeutics
V Kumar - European journal of cell biology, 2018 - Elsevier
Sepsis has always been considered as a big challenge for pharmaceutical companies in
terms of discovering and designing new therapeutics. The pathogenesis of sepsis involves …
terms of discovering and designing new therapeutics. The pathogenesis of sepsis involves …
Interleukin-7 (IL-7) treatment accelerates neutrophil recruitment through γδ T-cell IL-17 production in a murine model of sepsis
KR Kasten, PS Prakash, J Unsinger… - Infection and …, 2010 - Am Soc Microbiol
The sepsis syndrome represents an improper immune response to infection and is
associated with unacceptably high rates of mortality and morbidity. The interactions between …
associated with unacceptably high rates of mortality and morbidity. The interactions between …
[HTML][HTML] Early alterations of the innate and adaptive immune statuses in sepsis according to the type of underlying infection
Introduction Although major changes of the immune system have been described in sepsis,
it has never been studied whether these may differ in relation to the type of underlying …
it has never been studied whether these may differ in relation to the type of underlying …
T cells are potent early mediators of the host response to sepsis
KR Kasten, J Tschöp, SG Adediran, DA Hildeman… - Shock, 2010 - journals.lww.com
The complex immune response associated with sepsis results in a high rate of morbidity and
mortality, despite substantial basic science and clinical advances. Most of the research has …
mortality, despite substantial basic science and clinical advances. Most of the research has …
Sepsis, leukocytes, and nitric oxide (NO): an intricate affair
CF Fortin, PP McDonald, T Fülöp, O Lesur - Shock, 2010 - journals.lww.com
Sepsis is exceedingly burdensome for hospital intensive care unit caregivers, and its
incidence, as well as sepsis-related deaths, is increasing steadily. Sepsis is characterized …
incidence, as well as sepsis-related deaths, is increasing steadily. Sepsis is characterized …
[HTML][HTML] Associations of T helper 1, 2, 17 and regulatory T lymphocytes with mortality in severe sepsis
HP Wu, K Chung, CY Lin, BY Jiang, DY Chuang… - Inflammation …, 2013 - Springer
Objective and design T helper 17 (Th17) and regulatory T (T reg) lymphocytes might play
important roles in patients with severe sepsis. The association of Th17 or T reg lymphocytes …
important roles in patients with severe sepsis. The association of Th17 or T reg lymphocytes …
The role of interferon-γ in the pathogenesis of acute intra-abdominal sepsis
CR Romero, DS Herzig, A Etogo… - Journal of leukocyte …, 2010 - academic.oup.com
IFNγ produced by intraperitoneal myeloid and NK cells during cecal ligation/puncture-
induced septic shock facilitates myeloid cell activation yet blockade of IFNγ does not …
induced septic shock facilitates myeloid cell activation yet blockade of IFNγ does not …
[HTML][HTML] Risk factors for nosocomial infection among hospitalised severe influenza A (H1N1) pdm09 patients
F Zhou, H Li, L Gu, M Liu, C Xue, B Cao, C Wang - Respiratory medicine, 2018 - Elsevier
Background and objective Nosocomial infections following influenza are important causes of
death, requiring early implementation of preventive measures, but predictors for nosocomial …
death, requiring early implementation of preventive measures, but predictors for nosocomial …
[HTML][HTML] CD4 and CD8 T cell memory interactions alter innate immunity and organ injury in the CLP sepsis model
MD Taylor, TD Fernandes, AP Kelly… - Frontiers in …, 2020 - frontiersin.org
The role of T cell memory in sepsis is poorly understood. Recent work has demonstrated that
mice exposed to frequent antigenic stimulation, in contrast to laboratory mice, better …
mice exposed to frequent antigenic stimulation, in contrast to laboratory mice, better …