CD9 belongs to the tetraspanin superfamily. Depending on the cell type and associated
molecules, CD9 has a wide variety of biological activities such as cell adhesion, motility …

Despite major advances in the understanding and treatment of hepatitis C, a preventive
vaccine remains elusive. The marked genetic diversity and multiple mechanisms of …

Encouraging efficacy data have been obtained in the hepatitis C virus (HCV) chimpanzee
model using prophylactic vaccines comprising adjuvanted recombinant envelope …

It is well established that full activation of T cells that recognize antigens requires additional
signals. These second signals are generated by the interaction of costimulatory ligands …

The hepatitis C virus (HCV) is a global public health problem affecting approximately 2% of
the human population. The majority of HCV infections (more than 70%) result in life-long …

The identification of novel targets and strategies for therapy of microbial infections is an area
of intensive research due to the failure of conventional vaccines or antibiotics to combat both …

Objective: To quantify serum levels of intercellular adhesion molecule-1 (sICAM-1) and
vascular cell adhesion molecule-1 (sVCAM-1) in HIV/HCV coinfected patients to examine …

CD81 is a tetraspanin cell surface protein that regulates CD19 expression in B lymphocytes
and enables hepatitis C virus infection of human cells. Immunohistologic analysis in normal …

Cluster of differentiation 81 (CD81) is a widely expressed tetraspanin molecule that
physically associates with CD4 and CD8 on the surface of human T cells. Coengagement of …

The treatment of patients with chronic hepatitis C virus (HCV) infection has changed
tremendously over the past 2 years, with an increasing variety of all-oral direct-acting …