Drug discovery and development is a time-consuming process that involves identifying,
designing, and testing new drugs to address critical medical needs. In recent years, machine …

The human microbiome is associated with human health and disease. Exogenous
compounds, including pharmaceutical products, are also known to be affected by the …

The dosing of tacrolimus, which forms the backbone of immunosuppressive therapy after
kidney transplantation, is complex. This is due to its variable pharmacokinetics (both …

Gut microbiota is often modified after kidney transplantation. This principally happens in the
first period after transplantation. Antibiotics and, most of all, immunosuppressive drugs are …

IgA nephropathy, presently recognized as the foremost primary glomerular disorder,
emerges as a principal contributor to renal failure globally, with its pathogenesis yet to be …

Background: Cardiovascular diseases (CVDs) continue to exert a substantial global
influence in specific areas due to population growth, aging, microbiota, and …

Introduction: The proposal for a revamped physical education curriculum in Ecuador
represents a significant shift in the education paradigm. This renewal aims to foster an open …

Genomics, proteomics and molecular biology lead to tremendous advances in all fields of
medical sciences. Among these the finding of biomarkers as non invasive indicators of …