Nanotechnology meets glioblastoma multiforme: Emerging therapeutic strategies

D Liu, X Dai, L Ye, H Wang, H Qian… - Wiley …, 2023 - Wiley Online Library
Glioblastoma multiforme (GBM) represents the most common and fatal form of primary
invasive brain tumors as it affects a great number of patients each year and has a median …

Nanoscale drug delivery systems in glioblastoma

Z Liu, X Ji, D He, R Zhang, Q Liu, T Xin - Nanoscale Research Letters, 2022 - Springer
Glioblastoma is the most aggressive cerebral tumor in adults. However, the current
pharmaceuticals in GBM treatment are mainly restricted to few chemotherapeutic drugs and …

Metronomic photodynamic therapy with conjugated polymer nanoparticles in glioblastoma tumor microenvironment

MD Caverzán, PM Oliveda, L Beaugé, RE Palacios… - Cells, 2023 - mdpi.com
Alternative therapies such as photodynamic therapy (PDT) that combine light, oxygen and
photosensitizers (PSs) have been proposed for glioblastoma (GBM) management to …

[HTML][HTML] Hypoxia alleviating platinum (IV)/chlorin e6-based combination chemotherapeutic-photodynamic nanomedicine for oropharyngeal carcinoma

M Paul, AM Itoo, B Ghosh, S Biswas - Journal of Photochemistry and …, 2023 - Elsevier
Hypoxia is an important pathological hallmark of the tumor microenvironment, associated
with metabolic alterations, cell proliferation, aggressiveness, metastasis, and therapy …

Conjugated polymer nanoparticles for tumor theranostics

T Li, M Wu, Q Wei, D Xu, X He, J Wang, J Wu… - …, 2023 - ACS Publications
Water-dispersible conjugated polymer nanoparticles (CPNs) have demonstrated great
capabilities in biological applications, such as in vitro cell/subcellular imaging and …

Selective photo-assisted eradication of Triple-Negative breast cancer cells through aptamer decoration of doped conjugated polymer nanoparticles

LE Ibarra, S Camorani, L Agnello, E Pedone, L Pirone… - Pharmaceutics, 2022 - mdpi.com
Photodynamic therapy (PDT) may be an excellent alternative in the treatment of breast
cancer, mainly for the most aggressive type with limited targeted therapies such as triple …

Photosensitizers for Photodynamic Therapy of Brain Cancers—A Review

D Bartusik-Aebisher, P Woźnicki, K Dynarowicz… - Brain Sciences, 2023 - mdpi.com
On average, there are about 300,000 new cases of brain cancer each year. Studies have
shown that brain and central nervous system tumors are among the top ten causes of death …

[HTML][HTML] Photodynamic therapy for glioblastoma: a light at the end of the tunnel

M Miretti, MAG Graglia, AI Suárez, CG Prucca - Journal of Photochemistry …, 2023 - Elsevier
Glioblastomas (GBM) are considered one of the most aggressive tumors of the central
nervous system. The standard treatment for GBM-diagnosed patients implies surgery …

[HTML][HTML] Light-activated green drugs: How we can use them in photodynamic therapy and mass-produce them with biotechnological tools

E Foresto, P Gilardi, LE Ibarra, IS Cogno - Phytomedicine Plus, 2021 - Elsevier
Photodynamic therapy (PDT) is a promising therapeutic approach to manage the resolution
of cancer. Plants in nature are one of the potential sources for obtaining new …

[HTML][HTML] Iron oxide incorporated conjugated polymer nanoparticles for simultaneous use in magnetic resonance and fluorescent imaging of brain tumors

N Arias-Ramos, LE Ibarra, M Serrano-Torres, B Yagüe… - Pharmaceutics, 2021 - mdpi.com
Conjugated polymer nanoparticles (CPNs) have emerged as advanced polymeric
nanoplatforms in biomedical applications by virtue of extraordinary properties including high …