[HTML][HTML] Fibrosis and hepatic regeneration mechanism

E Zuñiga-Aguilar… - Translational …, 2022 - ncbi.nlm.nih.gov
Liver cirrhosis is the final stage of continuous hepatic inflammatory activity derived by viral,
metabolic or autoimmune origin. In the last years, cirrhosis was considered a unique and …

Transarterial drug delivery for liver cancer: numerical simulations and experimental validation of particle distribution in patient-specific livers

T Bomberna, GA Koudehi, C Claerebout… - Expert Opinion on …, 2021 - Taylor & Francis
Background: Transarterial therapies are routinely used for the locoregional treatment of
unresectable hepatocellular carcinoma (HCC). However, the impact of clinical parameters …

[HTML][HTML] Mesoscale visualization of three-dimensional microvascular architecture and immunocyte distribution in intact mouse liver lobes

Z Liu, M Xu, S Huang, Q Pan, C Liu, F Zeng, Z Fan… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rational: The complex vascular architecture and diverse immune cells of the liver are critical
for maintaining liver homeostasis. However, quantification of the network of liver vasculature …

Ultrasensitive US microvessel imaging of hepatic microcirculation in the cirrhotic rat liver

W Zhang, C Huang, T Yin, X Miao, H Deng, R Zheng… - Radiology, 2022 - pubs.rsna.org
Background Liver microcirculation dysfunction plays a vital role in the occurrence and
development of liver diseases, and thus, there is a clinical need for in vivo, noninvasive, and …

Fluid mechanics approach to perfusion quantification: vasculature computational fluid dynamics simulation, quantitative transport mapping (QTM) analysis of dynamics …

Q Zhang, X Luo, L Zhou, TD Nguyen… - IEEE Transactions …, 2022 - ieeexplore.ieee.org
Objective: We quantify liver perfusion using quantitative transport mapping (QTM) method
that is free of arterial input function (AIF). QTM method is validated in a vasculature …

Corrosion casting in anatomy: Visualizing the architecture of hollow structures and surface details

P Cornillie, C Casteleyn, C von Horst… - Anatomia, histologia …, 2019 - Wiley Online Library
Corrosion casting is the technique by which a solid, negative replica is created from a hollow
anatomical structure and liberated from its surrounding tissues. For centuries, different types …

Phenotypic characterization of liver tissue heterogeneity through a next-generation 3D single-cell atlas

D Martínez-Torres, V Maldonado, C Pérez-Gallardo… - Scientific reports, 2024 - nature.com
Abstract Three-dimensional (3D) geometrical models are potent tools for quantifying
complex tissue features and exploring structure–function relationships. However, these …

Multiscale reconstruction of various vessels in the intact murine liver lobe

Q Zhang, A Li, S Chen, J Yuan, T Jiang, X Li… - Communications …, 2022 - nature.com
The liver contains a variety of vessels and participates in miscellaneous physiological
functions. While past studies generally focused on certain hepatic vessels, we …

Quantification of the whole lymph node vasculature based on tomography of the vessel corrosion casts

M Jafarnejad, AZ Ismail, D Duarte, C Vyas… - Scientific Reports, 2019 - nature.com
Lymph nodes (LN) are crucial for immune function, and comprise an important interface
between the blood and lymphatic systems. Blood vessels (BV) in LN are highly specialized …

Closed-loop lumped parameter modeling of hemodynamics during cirrhogenesis in rats

C Audebert, G Peeters, P Segers… - IEEE Transactions …, 2018 - ieeexplore.ieee.org
Objective: Cirrhosis is the common end stage of any given chronic liver disease, developing
after persistent destruction and regeneration of parenchymal liver cells. The associated …