DICER1 syndrome is a rare genetic disorder that predisposes individuals to multiple cancer
types. Through mutations of the gene encoding the endoribonuclease, Dicer, DICER1 …

DICER1 syndrome is a pleiotropic tumor predisposition syndrome characterized by a
distinctive constellation of neoplastic and dysplastic lesions, which are generally rare and …

Objective: To develop evidence-based recommendations for safe, effective, and appropriate
thyroidectomy. Background: Surgical management of thyroid disease has evolved …

DICER1 syndrome is a rare tumor predisposition syndrome with manifestations that
predominantly affect children and young adults. The syndrome is typically caused by …

Gynecologic sarcomas are uncommon neoplasms, the majority occurring in the uterus. Due
to the diverse nature of these, the description of “new” morphological types and the rarity of …

Primary lung tumors in children are rare, with a narrow range of diagnostic considerations.
However, the overlapping imaging appearances of these tumors necessitate attention to key …

DICER1 syndrome is a rare genetic disorder that predisposes to a wide spectrum of tumors.
Developing surveillance protocols for this syndrome is challenging because uncertainty …

Context Pituitary blastoma is a rare, dysontogenetic hypophyseal tumor of infancy first
described in 2008, strongly suggestive of DICER1 syndrome. Objective This work aims to …

DICER1 syndrome is a highly pleiotropic tumor predisposition syndrome that has been
increasingly recognized in the last 10 years. Diseases in the syndrome result from mutations …

Pineoblastoma is a rare pediatric cancer induced by germline mutations in the tumor
suppressors RB1 or DICER1. Presence of leptomeningeal metastases is indicative of poor …