A new flavanone isolated from rhizoma Smilacis glabrae and the structural requirements of its derivatives for preventing immunological hepatocyte damage

T Chen, J Li, J Cao, Q Xu, K Komatsu… - Planta Medica, 1999 - thieme-connect.com
From the rhizome of Smilax glabra Roxb., a new flavanone was isolated and named as
smitilbin (1), together with 6 known compounds, engeletin (2), astilbin (3), dihydroquercetin …

Astilbin selectively induces dysfunction of liver-infiltrating cells—novel protection from liver damage

Q Xu, F Wu, J Cao, T Chen, J Jiang, I Saiki… - European Journal of …, 1999 - Elsevier
The present study aimed to examine the effect of astilbin, a flavanoid, on liver injury. When
administered during the effector but not induction phase, astilbin significantly decreased the …

Ruscogenin glycoside (Lm-3) isolated from Liriope muscari improves liver injury by dysfunctioning liver-infiltrating lymphocytes

F Wu, J Cao, J Jiang, B Yu, Q Xu - Journal of pharmacy and …, 2001 - academic.oup.com
The effects of ruscogenin 1-O-[β-d-glucopyranosyl (1→ 2)][β-d-xylopyranosyl (1→ 3)]-β-d-
fucopyranoside (Lm-3) and its aglycone, ruscogenin, on liver injury induced in mice by …

Astilbin selectively facilitates the apoptosis of interleukin-2-dependent phytohemagglutinin-activated Jurkat cells

R Yan, Q Xu - Pharmacological Research, 2001 - Elsevier
The present study examined the relationship between the activation of T cells and the
apoptosis-facilitating effect of astilbin on them. By the stimulation of PHA, a remarkable IL-2 …

Alleviating effects of si-ni-san, a traditional Chinese prescription, on experimental liver injury and its mechanisms

J Jiang, C Zhou, Q Xu - Biological and Pharmaceutical Bulletin, 2003 - jstage.jst.go.jp
MATERIALS AND METHODS Animals Four-to six-week-old Kunming strain of mice were
obtained from the Experimental Animal Center of China Pharmaceutical University (Nanjing …

[PDF][PDF] 四逆散改善细胞免疫性肝损伤作用机理研究

周春祥, 徐强, 曹劲松, 蒋洁云, 吴斐华, 王利津… - 2002 - molpharm.nju.edu.cn
目的: 通过对四逆散改善细胞免疫性肝损伤作用机理的研究, 揭示该方在临床肝炎治疗中的作用
特色. 方法: 运用Picryl chloride 致迟发性变态反应(PCl-DTH) 肝损伤动物模型及细胞生物学 …

A novel role of alkaline phosphatase in protection from immunological liver injury in mice

Q Xu, Z Lu, X Zhang - Liver, 2002 - Wiley Online Library
Aims/Background: Little is known about the role of alkaline phosphatase (AP) in liver
diseases, except for its elevation in jaundice or cholestasis. Its substrate, endotoxin, is …

[PDF][PDF] 白鲜皮水提物改善迟发型变态反应性肝损伤的作用机理

陆朝华, 曹劲松, 凡华, 徐强 - 1999 - molpharm.nju.edu.cn
摘要白鲜皮水提物能作用于2, 4, 6-三硝基氯苯所致迟发型变态反应的效应相,
有效地改善迟发型变态反应性肝损伤, 在肝损伤12 h 分离的肝非实质细胞和肝细胞共培养体系 …

[PDF][PDF] 四逆散及其各组成中药对实验性肝损伤的影响CJNM

蒋洁云, 徐强 - 中国天然药物, 2004 - molpharm.nju.edu.cn
目的: 对四逆散进行初步拆方研究, 探讨组成四逆散的各单味中药在全方中所起的作用. 方法:
运用CCl4 体外致肝细胞损伤及2, 4, 6-三硝基氯苯(PCl) 致迟发型变态反应(PCl-DTH) …

Nitric oxide inhibits T cell adhesion and migration by down-regulation of β1-integrin expression in immunologically liver-injured mice

Y Sun, J Liu, F Qian, Q Xu - International immunopharmacology, 2006 - Elsevier
Our previous study has reported that nitric oxide (NO) exerts a protective role in
immunologically liver-injured mice induced by delayed-type hypersensitivity to picryl …