Biology of chemokine and classical chemoattractant receptors: differential requirements for adhesion-triggering versus chemotactic responses in lymphoid cells.
JJ Campbell, S Qin, KB Bacon, CR Mackay… - The Journal of cell …, 1996 - rupress.org
Several chemoattractant receptors can support agonist-induced, integrin-dependent arrest
of rolling neutrophils in inflamed venules in vivo, as well as subsequent crawling into …
of rolling neutrophils in inflamed venules in vivo, as well as subsequent crawling into …
Genetically detoxified pertussis toxin (PT-9K/129G): implications for immunization and vaccines
A Seubert, U D'Oro, M Scarselli… - Expert review of vaccines, 2014 - Taylor & Francis
Pertussis toxin (PT) is one of the major virulence factors of Bordetella pertussis and the
primary component of all pertussis vaccines available to date. Because of its various …
primary component of all pertussis vaccines available to date. Because of its various …
The pharmacology of T cell apoptosis
G Kroemer - Advances in immunology, 1995 - Elsevier
L'inferno dei viventi non è qualcosa che sarà; se ce n'è uno, è quello che é gia qui, l'inferno
che abitiamo tutti i giorni, che formiamo stando insieme. Due modi ci sono per non soffrirne …
che abitiamo tutti i giorni, che formiamo stando insieme. Due modi ci sono per non soffrirne …
Rapid G protein-regulated activation event involved in lymphocyte binding to high endothelial venules.
RF Bargatze, EC Butcher - The Journal of experimental medicine, 1993 - rupress.org
The homing of blood borne lymphocytes into lymph nodes and Peyer's patches is mediated
in part by recognition and binding to specialized high endothelial venules (HEV). Here we …
in part by recognition and binding to specialized high endothelial venules (HEV). Here we …
Whole-cell but not acellular pertussis vaccines induce convulsive activity in mice: evidence of a role for toxin-induced interleukin-1β in a new murine model for …
S Donnelly, CE Loscher, MA Lynch… - Infection and …, 2001 - Am Soc Microbiol
Immunization with the whole-cell pertussis vaccine (Pw), while effective at preventing
whooping cough in infants, has been associated with local, systemic, and neuronal …
whooping cough in infants, has been associated with local, systemic, and neuronal …
Pertussis: the trials and tribulations of old and new pertussis vaccines
JD Cherry - Vaccine, 1992 - Elsevier
The mortality from pertussis in unvaccinated infants is significantly greater than that reported.
Most present day whole-cell pertussis vaccines are efficacious. Although they cause …
Most present day whole-cell pertussis vaccines are efficacious. Although they cause …
Role of pertussis toxin A subunit in neutrophil migration and vascular permeability
The anti-inflammatory activity of pertussis toxin (Ptx) was compared to that of a noncatalytic
mutant of pertussis toxin (9K/129G; Ptxm), which contains two amino acid substitutions in the …
mutant of pertussis toxin (9K/129G; Ptxm), which contains two amino acid substitutions in the …
Development of vaccines at the time of COVID-19
In December 2019, a working group of the European Academy of Microbiology assembled
to discuss various aspects of vaccines and vaccinations. The meeting was organised by …
to discuss various aspects of vaccines and vaccinations. The meeting was organised by …
Comparison of the conformation, hydrophobicity, and model membrane interactions of diphtheria toxin to those of formaldehyde-treated toxin (diphtheria toxoid) …
R Paliwal, E London - Biochemistry, 1996 - ACS Publications
Toxoids are inactivated protein toxins that are used in vaccines. The behavior of diphtheria
toxin reacted with formaldehyde (diphtheria toxoid) was compared to that of diphtheria toxin …
toxin reacted with formaldehyde (diphtheria toxoid) was compared to that of diphtheria toxin …
Construction of a diphtheria toxin A fragment-C180 peptide fusion protein which elicits a neutralizing antibody response against diphtheria toxin and pertussis toxin
JT Barbieri, D Armellini, J Molkentin… - Infection and …, 1992 - Am Soc Microbiol
A genetically engineered gene fusion was constructed which encoded a nontoxic derivative
of the A fragment of diphtheria toxin joined to the C180 peptide of the S1 subunit of pertussis …
of the A fragment of diphtheria toxin joined to the C180 peptide of the S1 subunit of pertussis …