Elemene Antitumor Drugs Development Based on “Molecular Compatibility Theory” and Clinical Application: A Retrospective and Prospective Outlook
Elemene, derived from Curcuma wenyujin, one of the “8 famous genuine medicinal
materials of Zhejiang province,” exhibits remarkable antitumor activity. It has gained wide …
materials of Zhejiang province,” exhibits remarkable antitumor activity. It has gained wide …
Design, synthesis and biological evaluation of novel histone deacetylase (HDAC) inhibitors derived from β-elemene scaffold
Y Gao, J Duan, X Dang, Y Yuan, Y Wang… - Journal of Enzyme …, 2023 - Taylor & Francis
Abstract β-Elemene is the major active ingredient of TCM anticancer drug elemene extracts.
To further improve its antitumor activity and poor solubility, a polar HDACi pharmacophore …
To further improve its antitumor activity and poor solubility, a polar HDACi pharmacophore …
[图书][B] Elemene antitumor drugs: Molecular compatibility theory and its applications in new drug development and clinical practice
T Xie - 2022 - books.google.com
Elemene Antitumor Drugs: Molecular Compatibility Theory and its Applications in New Drug
Development and Clinical Practice introduces natural anti-tumor drug elemene and …
Development and Clinical Practice introduces natural anti-tumor drug elemene and …
Combination of chemotherapy and gaseous signaling molecular therapy: Novel β‐elemene nitric oxide donor derivatives against leukemia
J Zhu, X Jiang, X Luo, R Zhao, J Li… - Drug Development …, 2023 - Wiley Online Library
This study aimed to design and synthesize active hybrids of β‐elemene and nitric oxide (NO)
donor pharmacophore as potential agents for treating leukemia. Derivatives reported herein …
donor pharmacophore as potential agents for treating leukemia. Derivatives reported herein …