Feasibility of intranasal human milk as stem cell therapy in preterm infants with intraventricular hemorrhage
R Hoban, A Gallipoli, M Signorile, P Mander… - Journal of …, 2024 - nature.com
Objective Intraventricular hemorrhage (IVH) is a common cause of preterm brain injury.
Fresh parent's own milk (POM) contains pluripotent stem cells (SCs) that produce neuronal …
Fresh parent's own milk (POM) contains pluripotent stem cells (SCs) that produce neuronal …
Umbilical cord-derived mesenchymal stromal cell therapy to prevent the development of neurodevelopmental disorders related to low birth weight
M Tsuji, T Mukai, Y Sato, Y Azuma, S Yamamoto… - Scientific Reports, 2023 - nature.com
Low birth weight (LBW) increases the risk of neurodevelopmental disorders (NDDs) such as
attention-deficit/hyperactive disorder and autism spectrum disorder, as well as cerebral …
attention-deficit/hyperactive disorder and autism spectrum disorder, as well as cerebral …
Establishment of a novel fetal growth restriction model and development of a stem-cell therapy using umbilical cord-derived mesenchymal stromal cells
Fetal growth restriction (FGR) is a major complication of prenatal ischemic/hypoxic exposure
and affects 5%–10% of pregnancies. It causes various disorders, including …
and affects 5%–10% of pregnancies. It causes various disorders, including …
Nonhematopoietic Umbilical Cord Blood Stem Cell Administration Improves Long-term Neurodevelopment After Periventricular-Intraventricular Hemorrhage in …
RB Rao, ML Shiao, KM Ennis-Czerniak… - Cell …, 2023 - journals.sagepub.com
Periventricular-intraventricular hemorrhage (PIVH) is common in extremely low gestational
age neonates (ELGAN) and leads to motor and behavioral impairments. Currently there is …
age neonates (ELGAN) and leads to motor and behavioral impairments. Currently there is …
[HTML][HTML] Mesenchymal stromal cells: cell-based therapies for traumatic central nervous system injuries
T Mukai, K Sei, T Nagamura-Inoue - Journal of Integrative …, 2022 - imrpress.com
Traumatic central nervous system (CNS) injury often causes irreversible impairment, and
new alternative therapies for the treatment of CNS injury and sequelae are expected to be …
new alternative therapies for the treatment of CNS injury and sequelae are expected to be …
Challenges and research progress of the use of mesenchymal stem cells in the treatment of ischemic stroke
J Jiang, Y Wang, B Liu, X Chen, S Zhang - Brain and Development, 2018 - Elsevier
Abstract Cerebral Ischemic Stroke (CIS) has become a hot issue in medical research
because of the diversity of risk factors and the uncertainty of prognosis. In the field of …
because of the diversity of risk factors and the uncertainty of prognosis. In the field of …
Umbilical cord mesenchymal stem cells derived neurospheres promote long-term functional recovery but aggravate acute phase inflammation in experimental stroke
J Hu, Y Chang, C Peng, S Huang, G Li, H Li - Neuroscience, 2022 - Elsevier
Human umbilical cord mesenchymal stem cells (UC-MSCs) transplantation has been shown
to ameliorate intracerebral hemorrhage (ICH) in animal and clinical studies. We previously …
to ameliorate intracerebral hemorrhage (ICH) in animal and clinical studies. We previously …
Emerging therapies for brain recovery after IVH in neonates: cord blood derived mesenchymal stem cells (MSC) and unrestricted somatic stem cells (USSC)
G Vinukonda, EF La Gamma - Seminars in Perinatology, 2022 - Elsevier
In this report, we summarize evidence on mechanisms of injury after intraventricular
hemorrhage resulting in post-hemorrhagic white matter injury and hydrocephalus and …
hemorrhage resulting in post-hemorrhagic white matter injury and hydrocephalus and …
Pharmacological neuroprotection of the preterm brain: current evidence and perspectives
T Siahanidou, C Spiliopoulou - American Journal of …, 2022 - thieme-connect.com
Despite improvements in viability, the long-term neurodevelopmental outcomes of preterm
babies remain serious concern as a significant percentage of these infants develop …
babies remain serious concern as a significant percentage of these infants develop …
[HTML][HTML] Potential therapeutic applications of stem cell therapy for neonatal hypoxic-ischaemic brain injury
A del Pozo, M Villa, J Martínez-Orgado - Neurology Perspectives, 2022 - Elsevier
Introduction and objectives Neonatal hypoxic-ischaemic brain injury is one of the main
known causes of cerebral palsy, the most frequent and severe form of motor disability in …
known causes of cerebral palsy, the most frequent and severe form of motor disability in …