Do lifestyles influence the presence of promiscuous enzymes in bacteria and Archaea metabolism?
MA Martínez-Núñez, E Pérez-Rueda - Sustainable Chemical Processes, 2016 - Springer
The adequacy of an organism to the environment depends in part on its ability to modify its
repertoire of cellular components, such as transporters, regulatory proteins and metabolic …
repertoire of cellular components, such as transporters, regulatory proteins and metabolic …
Racemization study on different N-acetylamino acids by a recombinant N-succinylamino acid racemase from Geobacillus kaustophilus CECT4264
J Pozo-Dengra, AI Martínez-Gómez… - Process …, 2009 - Elsevier
N-Succinylamino acid racemase (NSAAR) with N-acylamino acid racemase (NAAAR)
activity together with a d-or l-aminoacylase allows the total transformation of N-acetylamino …
activity together with a d-or l-aminoacylase allows the total transformation of N-acetylamino …
Molecular evolution of proadrenomedullin N-terminal 20 peptide (PAMP): evidence for gene co-option
A Martínez, JA Bengoechea, F Cuttitta - Endocrinology, 2006 - academic.oup.com
Posttranslational processing of proadrenomedullin generates two biologically active
peptides, adrenomedullin (AM) and proadrenomedullin N-terminal 20 peptide (PAMP) …
peptides, adrenomedullin (AM) and proadrenomedullin N-terminal 20 peptide (PAMP) …
Open Issues for Protein Function Assignment in Haloferax volcanii and Other Halophilic Archaea
F Pfeiffer, M Dyall-Smith - Genes, 2021 - mdpi.com
Background: Annotation ambiguities and annotation errors are a general challenge in
genomics. While a reliable protein function assignment can be obtained by experimental …
genomics. While a reliable protein function assignment can be obtained by experimental …
Role of an Active Site Loop in the Promiscuous Activities of Amycolatopsis sp. T-1-60 NSAR/OSBS
The o-succinylbenzoate synthase (OSBS) family is part of the functionally diverse enolase
superfamily. Many proteins in one branch of the OSBS family catalyze both OSBS and N …
superfamily. Many proteins in one branch of the OSBS family catalyze both OSBS and N …
MosA, a protein implicated in rhizopine biosynthesis in Sinorhizobium meliloti L5-30, is a dihydrodipicolinate synthase
PH Tam, CP Phenix, DRJ Palmer - Journal of molecular biology, 2004 - Elsevier
MosA is a gene product encoded on a pSym megaplasmid of Sinorhizobium meliloti L5-30.
The gene is part of an operon reported to be essential for the synthesis of the rhizopine 3-O …
The gene is part of an operon reported to be essential for the synthesis of the rhizopine 3-O …
Predictive model for epoxide hydrolase-generated stereochemistry in the biosynthesis of nine-membered enediyne antitumor antibiotics
Nine-membered enediyne antitumor antibiotics C-1027, neocarzinostatin (NCS), and
kedarcidin (KED) possess enediyne cores to which activity-modulating peripheral moieties …
kedarcidin (KED) possess enediyne cores to which activity-modulating peripheral moieties …
Promiscuity of Exiguobacterium sp. AT1b o-succinylbenzoate synthase illustrates evolutionary transitions in the OSBS family
AM Brizendine, D Odokonyero, AW McMillan… - Biochemical and …, 2014 - Elsevier
Catalytic promiscuity, which is the ability to catalyze more than one reaction in the same
active site, is thought to facilitate the evolution of new protein functions. Although many …
active site, is thought to facilitate the evolution of new protein functions. Although many …
Simultaneous analysis of enantiomeric composition of amino acids and N‐acetyl‐amino acids by enantioselective chromatography
YP Yu, SH Wu - Chirality: The Pharmacological, Biological, and …, 2001 - Wiley Online Library
Among the three chiral columns, CHIROBIOTIC T™, CHIRLPAK WH, and CHIRALCEL OD‐
R, tested for the separation of racemic amino acids and N‐acetyl‐amino acids, only …
R, tested for the separation of racemic amino acids and N‐acetyl‐amino acids, only …
Cloning of the N-acylamino acid racemase gene from Amycolatopsis azurea and biochemical characterization of the gene product
SC Su, CY Lee - Enzyme and microbial technology, 2002 - Elsevier
A gene encoding N-acylamino acid racemase (NAAAR) from Amycolatopsis azurea
CCRC13413 was cloned. An analysis of its sequence revealed an open reading frame …
CCRC13413 was cloned. An analysis of its sequence revealed an open reading frame …