Importance Intravenous iron is recommended by many clinical guidelines based largely on
its effectiveness in reducing anemia. However, the association with important safety …

Non-anaemic iron deficiency (NAID) is a strategic target in cardiovascular medicine because
of its association with a range of adverse effects in various conditions. Endeavours to tackle …

Iron is an essential nutrient for oxygen supply and aerobic metabolism. Iron deficiency
impacts cellular respiration and mitochondrial energy metabolism, which can lead to …

Anaemia is common in older people, appears mainly due to iron deficiency and is
associated 1 with loss of well-being, reduced exercise capacity and increased all-cause and …

Iron deficiency impairs skeletal muscle metabolism. The underlying mechanisms are
incompletely characterised, but animal and human experiments suggest the involvement of …

Background Observational studies have found an association between iron deficiency
anemia (IDA) and chronic obstructive pulmonary disease (COPD) risk. However, whether …

Nutritional immunity is the sequestration of bioavailable trace metals such as iron, zinc and
copper by the host to limit pathogenicity by invading microorganisms. As one of the most …

Chronic obstructive pulmonary disease (COPD) is a prevalent lung condition associated
with significant morbidity and mortality. The management of COPD classically involves …

Introduction Iron deficiency affects exercise capacity because of the critical role iron plays in
the optimal functioning of skeletal muscle metabolism. We hypothesized that intravenous …

In COPD, anaemia is associated with increased morbidity, but the relationship between
haemoglobin over its entire observed range and morbidity is poorly understood. Such an …