[HTML][HTML] 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation
CT January, LS Wann, JS Alpert, H Calkins… - Circulation, 2014 - journals.lww.com
2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation | Circulation
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Unravelling the human genome–phenome relationship using phenome-wide association studies
Advances in genotyping technology have, over the past decade, enabled the focused
search for common genetic variation associated with human diseases and traits. With the …
search for common genetic variation associated with human diseases and traits. With the …
Genetic heritability of ischemic stroke and the contribution of previously reported candidate gene and genomewide associations
Background and Purpose—The contribution of genetics to stroke risk, and whether this
differs for different stroke subtypes, remainsuncertain. Genomewide complex trait analysis …
differs for different stroke subtypes, remainsuncertain. Genomewide complex trait analysis …
Common variants in KCNN3 are associated with lone atrial fibrillation
PT Ellinor, KL Lunetta, NL Glazer, A Pfeufer, A Alonso… - Nature …, 2010 - nature.com
Atrial fibrillation (AF) is the most common sustained arrhythmia. Previous studies have
identified several genetic loci associated with typical AF. We sought to identify common …
identified several genetic loci associated with typical AF. We sought to identify common …
Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke
International Stroke Genetics Consortium (ISGC)… - Nature …, 2012 - nature.com
Genetic factors have been implicated in stroke risk, but few replicated associations have
been reported. We conducted a genome-wide association study (GWAS) for ischemic stroke …
been reported. We conducted a genome-wide association study (GWAS) for ischemic stroke …
Lone atrial fibrillation: does it exist?
DG Wyse, IC Van Gelder, PT Ellinor, AS Go… - Journal of the American …, 2014 - jacc.org
The historical origin of the term “lone atrial fibrillation”(AF) predates by 60 years our current
understanding of the pathophysiology of AF, the multitude of known etiologies for AF, and …
understanding of the pathophysiology of AF, the multitude of known etiologies for AF, and …
Several common variants modulate heart rate, PR interval and QRS duration
Electrocardiographic measures are indicative of the function of the cardiac conduction
system. To search for sequence variants that modulate heart rate, PR interval and QRS …
system. To search for sequence variants that modulate heart rate, PR interval and QRS …
Atrial fibrillation: current knowledge and future directions in epidemiology and genomics
Atrial fibrillation (AF) is of public health importance and profoundly increases morbidity,
mortality, and healthrelated expenditures. Morbidities include the increased risks of …
mortality, and healthrelated expenditures. Morbidities include the increased risks of …
Association between familial atrial fibrillation and risk of new-onset atrial fibrillation
Context Although the heritability of atrial fibrillation (AF) is established, the contribution of
familial AF to predicting new-onset AF remains unknown. Objective To determine whether …
familial AF to predicting new-onset AF remains unknown. Objective To determine whether …
A rare variant in MYH6 is associated with high risk of sick sinus syndrome
Through complementary application of SNP genotyping, whole-genome sequencing and
imputation in 38,384 Icelanders, we have discovered a previously unidentified sick sinus …
imputation in 38,384 Icelanders, we have discovered a previously unidentified sick sinus …