Atrial fibrillation (AF), the most prevalent sustained cardiac arrhythmia, often coexists with
the related arrhythmia atrial flutter (AFL). Limitations in effectiveness and safety of current …

Рекомендации разработаны экспертами Российского кардиологического общества в
сотрудничестве с Всероссийским научным обществом специалистов по клинической …

Background—Atrial fibrillation (AF) affects> 30 million individuals worldwide and is
associated with an increased risk of stroke, heart failure, and death. AF is highly heritable …

Primary angle closure glaucoma (PACG) is a major cause of blindness worldwide. We
conducted a genome-wide association study (GWAS) followed by replication in a combined …

Cardiometabolic diseases contribute more to global morbidity and mortality than any other
group of disorders. Polygenic risk scores (PRSs), the weighted summation of individually …

Background The discovery of disease-associated loci through genome-wide association
studies (GWAS) is the leading genetic approach to the identification of novel biological …

Background: ZFHX3 (zinc finger homeobox 3), a gene that encodes a large transcription
factor, is at the second-most significantly associated locus with atrial fibrillation (AF), but its …

Objective: To investigate the influence of common and low-frequency genetic variants on the
risk of ischemic stroke (all IS) and etiologic stroke subtypes. Methods: We meta-analyzed 12 …

The etiology of ischemic stroke is multifactorial. Although receiving less emphasis, genetic
causes make a significant contribution to ischemic stroke genesis, especially in early-onset …

The management of atrial fibrillation (AF) has seen marked changes in past years, with the
introduction of new oral anticoagulants, new antiarrhythmic drugs, and the emergence of …