A guide to immunotherapy for COVID-19
FL van de Veerdonk, E Giamarellos-Bourboulis… - Nature medicine, 2022 - nature.com
Immune dysregulation is an important component of the pathophysiology of COVID-19. A
large body of literature has reported the effect of immune-based therapies in patients with …
large body of literature has reported the effect of immune-based therapies in patients with …
Repurposing the estrogen receptor modulator raloxifene to treat SARS-CoV-2 infection
The ongoing coronavirus disease 2019 (COVID-19) pandemic caused by the novel severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) necessitates strategies to identify …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) necessitates strategies to identify …
Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection
L Ma, SK Sahu, M Cano, V Kuppuswamy, J Bajwa… - Science …, 2021 - science.org
Complement activation has been implicated in the pathogenesis of severe SARS-CoV-2
infection. However, it remains to be determined whether increased complement activation is …
infection. However, it remains to be determined whether increased complement activation is …
Dysregulated Bradykinin: Mystery in the Pathogenesis of COVID‐19
The COVID‐19 pandemic is rapidly spreading, and health care systems are being
overwhelmed with the huge number of cases, with a good number of cases requiring …
overwhelmed with the huge number of cases, with a good number of cases requiring …
[HTML][HTML] Complement and COVID-19: Three years on, what we know, what we don't know, and what we ought to know
WM Zelek, RA Harrison - Immunobiology, 2023 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus was identified in
China in 2019 as the causative agent of COVID-19, and quickly spread throughout the …
China in 2019 as the causative agent of COVID-19, and quickly spread throughout the …
[HTML][HTML] Green tea polyphenol catechins inhibit coronavirus replication and potentiate the adaptive immunity and autophagy-dependent protective mechanism to …
CC Yang, CJ Wu, CY Chien, CT Chien - Antioxidants, 2021 - mdpi.com
Effective antiviral therapeutics are urgently required to fight severe acute respiratory
syndrome (SARS) caused by a SARS coronavirus (SARS-CoV). Because polyphenol …
syndrome (SARS) caused by a SARS coronavirus (SARS-CoV). Because polyphenol …
Severe COVID-19 infection associated with endothelial dysfunction induces multiple organ dysfunction: a review of therapeutic interventions
Y Matsuishi, BJ Mathis, N Shimojo, J Subrina, N Okubo… - Biomedicines, 2021 - mdpi.com
Since December 2019, the SARS-CoV-2 (COVID-19) pandemic has transfixed the medical
world. COVID-19 symptoms vary from mild to severe and underlying chronic conditions such …
world. COVID-19 symptoms vary from mild to severe and underlying chronic conditions such …
Non-alcoholic fatty liver disease and liver secretome
Metabolism of carbohydrates and lipids and protein degradation occurs in the liver and
contributes to the body's homeostasis by secreting a variety of mediators. Any imbalance in …
contributes to the body's homeostasis by secreting a variety of mediators. Any imbalance in …
Functional activity of the complement system in hospitalized COVID-19 patients: A prospective cohort study
P Charitos, IAFM Heijnen, A Egli, S Bassetti… - Frontiers in …, 2021 - frontiersin.org
Aims Although the exact factors promoting disease progression in COVID-19 are not fully
elucidated, unregulated activation of the complement system (CS) seems to play a crucial …
elucidated, unregulated activation of the complement system (CS) seems to play a crucial …
C1-inhibitor: structure, functional diversity and therapeutic development
E Karnaukhova - Current Medicinal Chemistry, 2022 - ingentaconnect.com
Human C1-Inhibitor (C1INH), also known as C1-esterase inhibitor, is an important
multifunctional plasma glycoprotein that is uniquely involved in a regulatory network of …
multifunctional plasma glycoprotein that is uniquely involved in a regulatory network of …