[HTML][HTML] Natural peptides for immunological regulation in cancer therapy: mechanism, facts and perspectives

Y Zhang, C Liu, C Wu, L Song - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Cancer incidence and mortality rates are increasing annually. Treatment with surgery,
chemotherapy and radiation therapy (RT) is unsatisfactory because many patients have …

Resveratrol for targeting the tumor microenvironment and its interactions with cancer cells

Q Mu, M Najafi - International immunopharmacology, 2021 - Elsevier
Tumor resistance to therapy modalities is one of the major challenges to the eradication of
cancer cells and complete treatment. Tumor includes a wide range of cancer and non …

Translational nanotherapeutics reprograms immune microenvironment in malignant pleural effusion of lung adenocarcinoma

Z Song, W Luo, H Zheng, Y Zeng… - Advanced Healthcare …, 2021 - Wiley Online Library
Malignant pleural effusion (MPE) remains a treatment bottleneck in advanced lung cancer,
due to its complicated microenvironments and “cold” immunity. Therefore, the search for …

Peptide-Based vaccine against breast cancer: Recent advances and prospects

ML Nordin, AK Azemi, AH Nordin, W Nabgan, PY Ng… - Pharmaceuticals, 2023 - mdpi.com
Breast cancer is considered the second-leading cancer after lung cancer and is the most
prevalent cancer among women globally. Currently, cancer immunotherapy via vaccine has …

Peptide vaccine from cancer-testis antigen ODF2 can potentiate the cytotoxic T lymphocyte infiltration through IL-15 in non-MSI-H colorectal cancer

R Shi, X Zhou, L Pang, M Wang, Y Li, C Chen… - Cancer Immunology …, 2023 - Springer
About 85% of patients with colorectal cancer (CRC) have the non-microsatellite instability-
high (non-MSI-H) subtype, and many cannot benefit from immune checkpoint blockade. A …

Biological Activity of Natural and Synthetic Peptides as Anticancer Agents

LV Bauso, V La Fauci, S Munaò, D Bonfiglio… - International Journal of …, 2024 - mdpi.com
Cancer is one of the leading causes of morbidity and death worldwide, making it a serious
global health concern. Chemotherapy, radiotherapy, and surgical treatment are the most …

[HTML][HTML] Design, synthesis and immunological evaluation of self-assembled antigenic peptides from dual-antigen targets: a broad-spectrum candidate for an effective …

W Shi, Q Qiu, Z Feng, Z Tong, W Guo… - … for ImmunoTherapy of …, 2021 - ncbi.nlm.nih.gov
Background Considering the narrow immune response spectrum of a single epitope, and
the nanoparticles (NPs) as a novel adjuvant can achieve efficient delivery of antigenic …

Immunomodulatory Peptides for Tumor Treatment

Y Song, L Lei, X Cai, H Wei… - Advanced Healthcare …, 2024 - Wiley Online Library
Peptides exhibit various biological activities, including biorecognition, cell targeting, and
tumor penetration, and can stimulate immune cells to elicit immune responses for tumor …

Development of novel self‐assembled vaccines based on tumour‐specific antigenic peptide and TLR2 agonist for effective breast cancer immunotherapy via …

W Shi, Z Tong, S Chen, Q Qiu, J Zhou, H Qian - Immunology, 2023 - Wiley Online Library
Vaccines based on tumour‐specific antigens are a promising approach for immunotherapy.
However, the clinical efficacy of tumour‐specific antigens is still challenging. Twelve …

Cell-penetrating peptides (CPPs) and peptide-drug conjugate systems (PDCs): site-specific delivery of bioactive (s) for effective breast cancer therapy

L Gautam, P Shrivastava, SP Vyas - Targeted Nanomedicine for Breast …, 2022 - Elsevier
In the present scenario, the role of the peptide as a targeting moiety is enhanced in different
types of cancer treatment which have biological actions based on their properties of …