The role of CREB and BDNF in neurobiology and treatment of Alzheimer's disease

M Amidfar, J de Oliveira, E Kucharska, J Budni, YK Kim - Life sciences, 2020 - Elsevier
Alzheimer's disease (AD) is the most common form of dementia worldwide. β-amyloid
peptide (Aβ) is currently assumed to be the main cause of synaptic dysfunction and cognitive …

Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders

MA Katzman, P Bleau, P Blier, P Chokka, K Kjernisted… - BMC psychiatry, 2014 - Springer
Background Anxiety and related disorders are among the most common mental disorders,
with lifetime prevalence reportedly as high as 31%. Unfortunately, anxiety disorders are …

Kecemasan remaja pada masa pandemi Covid-19

L Fitria, I Ifdil - Jurnal EDUCATIO: Jurnal Pendidikan Indonesia, 2020 - jurnal.iicet.org
This study aims to describe the level of anxiety experienced by adolescents during the covid-
19 pandemic. This research uses descriptive quantitative research methods. The population …

How does exercise reduce the rate of age-associated cognitive decline? A review of potential mechanisms

G Kennedy, RJ Hardman… - Journal of …, 2016 - journals.sagepub.com
The rate of age-associated cognitive decline varies considerably between individuals. It is
important, both on a societal and individual level, to investigate factors that underlie these …

Amyloid-β, anxiety, and cognitive decline in preclinical Alzheimer disease: a multicenter, prospective cohort study

RH Pietrzak, YY Lim, A Neumeister, D Ames… - JAMA …, 2015 - jamanetwork.com
Importance Alzheimer disease (AD) is now known to have a long preclinical phase in which
pathophysiologic processes develop many years, even decades, before the onset of clinical …

Exploring the impact of online social participation on loneliness in older adults: Evidence from The Canadian Longitudinal Study on Aging

S Goodarzi, J Jiang, M Head, X Lu - International Journal of Information …, 2023 - Elsevier
As individuals age, mental and physical impairment can emerge and impact their well-being.
Previous research on social participation in older adults has typically focused on specific …

[HTML][HTML] Coffee, tea, and caffeine consumption and prevention of late-life cognitive decline and dementia: a systematic review

F Panza, V Solfrizzi, MR Barulli, C Bonfiglio… - The journal of nutrition …, 2015 - Elsevier
A prolonged preclinical phase of more than two decades before the onset of dementia
suggested that initial brain changes of Alzheimer's disease (AD) and the symptoms of …

Interventions for generalized anxiety disorder in older adults: systematic review and meta-analysis

DC Gonçalves, GJ Byrne - Journal of anxiety disorders, 2012 - Elsevier
INTRODUCTION: Generalized anxiety disorder (GAD) is one of the most common anxiety
disorders in later life, with widespread consequences for individuals and society …

Executive function and other cognitive deficits are distal risk factors of generalized anxiety disorder 9 years later

NH Zainal, MG Newman - Psychological medicine, 2018 - cambridge.org
ObjectiveThe cognitive model (Hirsch & Mathews, 2012) and attentional control theory
(Eysenck & Derakshan, 2011) postulate that compromised executive function (EF) and other …

Late life anxiety is associated with decreased memory and executive functioning in community dwelling older adults

BP Yochim, AE Mueller, DL Segal - Journal of anxiety disorders, 2013 - Elsevier
This study assessed the degree to which anxiety and depression symptoms are associated
with memory and executive functioning among community-dwelling older adults (N= 120; M …