Molecular hydrogen is renowned as an odorless and colorless gas. The recommendations
developed by China suggest that the inhalation of hydrogen molecules is currently advised …

Chemokines and their receptors participate in many biological processes, including the
modulation of neuroimmune interactions. Approximately fifty chemokines are distinguished …

Background Pain is reported as the leading cause of disability in the common forms of
inflammatory arthritis conditions. Acting as a key player in nociceptive processing …

Traumatic brain injury (TBI) is the leading cause of death in the global population. Disturbed
inflammatory processes after TBI exacerbate secondary brain injury and contribute to …

Flaviviruses account for most arthropod-borne cases of human encephalitis in the world.
However, the exact mechanisms of injury to the central nervous system (CNS) during …

Painful diabetic neuropathy (PDN) is a severely debilitating chronic pain syndrome. Spinal
chemokine CXCL13 and its receptor CXCR5 were recently demonstrated to play a pivotal …

Many diseases, including cancer, can lead to neuropathic pain (NP). NP is one of the
accompanying symptoms of suffering in many conditions and the life quality of NP patient is …

Increasing evidence has indicated that activated glial cells releasing nociceptive factors,
such as interleukins and chemokines, are of key importance for neuropathic pain. Significant …

Neuropathic pain is a debilitating condition that affects millions of people worldwide.
Numerous studies indicate that this type of pain is a chronic condition with a complex …

Clinical management of neuropathic pain is unsatisfactory, mainly due to its resistance to the
effects of available analgesics, including opioids. Converging evidence indicates the …