Brief update on endocytosis of nanomedicines

S Patel, J Kim, M Herrera, A Mukherjee… - Advanced drug delivery …, 2019 - Elsevier
The complexity of nanoscale interactions between biomaterials and cells has limited the
realization of the ultimate vision of nanotechnology in diagnostics and therapeutics. As such …

Modification of extracellular vesicles by fusion with liposomes for the design of personalized biogenic drug delivery systems

M Piffoux, AKA Silva, C Wilhelm, F Gazeau, D Tareste - ACS nano, 2018 - ACS Publications
Extracellular vesicles (EVs) are recognized as nature's own carriers to transport
macromolecules throughout the body. Hijacking this endogenous communication system …

Cancer-derived exosomes loaded with ultrathin palladium nanosheets for targeted bioorthogonal catalysis

M Sancho-Albero, B Rubio-Ruiz, AM Pérez-López… - Nature …, 2019 - nature.com
The transformational impact of bioorthogonal chemistries has inspired new strategies for the
in vivo synthesis of bioactive agents through non-natural means. Among these, Pd catalysts …

Exosome biochemistry and advanced nanotechnology for next‐generation theranostic platforms

B Yang, Y Chen, J Shi - Advanced Materials, 2019 - Wiley Online Library
Recent marked technological advances in the field of exosome nanotechnology have
provided unprecedented opportunities to bloom the developments of exosome‐related …

Hydrogel encapsulation of mesenchymal stem cells and their derived exosomes for tissue engineering

P Khayambashi, J Iyer, S Pillai, A Upadhyay… - International journal of …, 2021 - mdpi.com
Tissue engineering has been an inveterate area in the field of regenerative medicine for
several decades. However, there remains limitations to engineer and regenerate tissues …

Bone‐a‐petite: engineering exosomes towards bone, osteochondral, and cartilage repair

HP Bei, PM Hung, HL Yeung, S Wang, X Zhao - Small, 2021 - Wiley Online Library
Recovery from bone, osteochondral, and cartilage injuries/diseases has been burdensome
owing to the damaged vasculature of large defects and/or avascular nature of cartilage …

Exosomal delivery of therapeutic modulators through the blood–brain barrier; promise and pitfalls

M Heidarzadeh, Y Gürsoy-Özdemir, M Kaya… - Cell & Bioscience, 2021 - Springer
Nowadays, a large population around the world, especially the elderly, suffers from
neurological inflammatory and degenerative disorders/diseases. Current drug delivery …

Exosomes and breast cancer drug resistance

X Dong, X Bai, J Ni, H Zhang, W Duan, P Graham… - Cell death & …, 2020 - nature.com
Drug resistance is a daunting challenge in the treatment of breast cancer (BC). Exosomes,
as intercellular communicative vectors in the tumor microenvironment, play an important role …

[HTML][HTML] Harnessing tissue-derived extracellular vesicles for osteoarthritis theranostics

B Yin, J Ni, CE Witherel, M Yang, JA Burdick, C Wen… - Theranostics, 2022 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is a prevalent chronic whole-joint disease characterized by low-grade
systemic inflammation, degeneration of joint-related tissues such as articular cartilage, and …

Exosomal cargo-loading and synthetic exosome-mimics as potential therapeutic tools

S Li, Z Lin, X Jiang, X Yu - Acta Pharmacologica Sinica, 2018 - nature.com
Exosomes are nano-sized vesicles that serve as mediators for intercellular communication
through the delivery of cargo, including protein, lipids, nucleic acids or other cellular …