Disruption of tissue function activates cellular stress which triggers a number of mechanisms
that protect the tissue from further damage. These mechanisms involve a number of …

Childhood cancer survivors (CCS) are at increased risk to develop metabolic syndrome
(MetS), diabetes, and cardiovascular disease. Common criteria underestimate adiposity and …

Background The survival rate of children and adolescents with acute lymphoblastic
leukemia (ALL) has progressively improved. However, ALL survivors often have adverse …

Neoplastic diseases in children are the second most frequent cause of death among the
young. It is estimated that 400,000 children worldwide will be diagnosed with cancer each …

Lymphoma is a serious malignant tumor that contains more than 70 different types and
seriously endangers the body's lymphatic system. The lymphatic system is the regulatory …

Lymphoma is a serious type of cancer, especially for adolescents and elder adults, although
this malignancy is quite rare compared with other types of cancer. The cause of this …

Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy. It is known
that deregulation of adipokine pathways is probably implicated in the ontogenesis of ALL …

Bone marrow (BM) microenvironment regulates and supports the production of blood cells
which are necessary to maintain homeostasis. In analogy to normal hematopoiesis …

Background: Acute lymphoblastic leukemia (ALL) is the most common cancer in children.
Abnormal expression of structural maintenance of chromosomes (SMC) 4 has been …

Cancer Research UK has reported that obesity is the second highest risk factor for
developing cancer after smoking. Studies suggest that almost three quarters of people are …