[HTML][HTML] PTEN, a barrier for proliferation and metastasis of gastric cancer cells: from molecular pathways to targeting and regulation

M Ashrafizadeh, M Najafi, HL Ang, ER Moghadam… - Biomedicines, 2020 - mdpi.com
Cancer is one of the life-threatening disorders that, in spite of excellent advances in
medicine and technology, there is no effective cure for. Surgery, chemotherapy, and …

[HTML][HTML] Non-canonical functions of spliceosome components in cancer progression

OM Ivanova, KS Anufrieva, AN Kazakova… - Cell Death & …, 2023 - nature.com
Dysregulation of pre-mRNA splicing is a common hallmark of cancer cells and it is
associated with altered expression, localization, and mutations of the components of the …

[HTML][HTML] Targeting LncRNA LLNLR-299G3. 1 with antisense oligonucleotide inhibits malignancy of esophageal squamous cell carcinoma cells in vitro and in vivo

LI Tian, Y Huang, B Zhang, YI Song, L Yang… - Oncology …, 2023 - ncbi.nlm.nih.gov
Accumulating evidence has indicated that long non-coding RNAs (lncRNAs) play critical
roles in the development and progression of cancers, including esophageal squamous cell …

Emerging role of lncRNA ELDR in development and cancer

S Sur, RB Ray - The FEBS Journal, 2022 - Wiley Online Library
Whole‐genome sequencing and transcriptome analysis revealed more than 90% of the
human genome transcribes noncoding RNAs including lncRNAs. From the beginning of the …

Long non‐coding RNA ELDR enhances oral cancer growth by promoting ILF 3‐cyclin E1 signaling

S Sur, H Nakanishi, R Steele, D Zhang… - EMBO …, 2020 - embopress.org
Oral squamous cell carcinoma (OSCC) is the sixth most common cancer with a 5‐year
overall survival rate of 50%. Thus, there is a critical need to understand the disease process …

[HTML][HTML] Identification of gene signatures and potential therapeutic targets for acquired chemotherapy resistance in gastric cancer patients

J Sun, J Zhao, Z Yang, Z Zhou, P Lu - Journal of gastrointestinal …, 2021 - ncbi.nlm.nih.gov
Background Gastric cancer (GC) is the most common type of gastrointestinal cancer, and
has been studied extensively. However, resistance to chemotherapeutic agents has become …

[HTML][HTML] Evaluation of the prognostic value of CBXs in gastric cancer patients

M He, L Yue, H Wang, F Yu, M Yu, P Ni, K Zhang… - Scientific Reports, 2021 - nature.com
Chromobox (CBX) proteins were suggested to exert epigenetic regulatory and
transcriptionally repressing effects on target genes and might play key roles in the …

[HTML][HTML] Metabolomic characterization reveals ILF2 and ILF3 affected metabolic adaptions in esophageal squamous cell carcinoma

B Zang, W Wang, Y Wang, P Li, T Xia, X Liu… - Frontiers in Molecular …, 2021 - frontiersin.org
Esophageal cancer (EC) is a common malignant disease in eastern countries. However, a
study of the metabolomic characteristics associated with other biological factors in …

[HTML][HTML] Comprehensive characterization of the epigenetic landscape in multiple myeloma

E Alaterre, S Ovejero, L Herviou, H de Boussac… - Theranostics, 2022 - ncbi.nlm.nih.gov
Background: Human multiple myeloma (MM) cell lines (HMCLs) have been widely used to
understand the molecular processes that drive MM biology. Epigenetic modifications are …

Prognostic and immunotherapeutic predictive value of interleukin enhancer-binding factor 3 in hepatocellular carcinoma: Integrated bioinformatics and experimental …

J Qiu, X Wu, Y Luo, Y Yao, X Zhang, B Pan, X Wang… - Gene, 2023 - Elsevier
Interleukin enhancer-binding factor 3 (ILF3) as an RNA-binding protein that plays a critical
role in the process of cancer and antiviral responses. However, no researcher has focused …