[HTML][HTML] RNA-based therapeutics: from antisense oligonucleotides to miRNAs
S Bajan, G Hutvagner - Cells, 2020 - mdpi.com
The first therapeutic nucleic acid, a DNA oligonucleotide, was approved for clinical use in
1998. Twenty years later, in 2018, the first therapeutic RNA-based oligonucleotide was …
1998. Twenty years later, in 2018, the first therapeutic RNA-based oligonucleotide was …
Updated review of advances in microRNAs and complex diseases: experimental results, databases, webservers and data fusion
MicroRNAs (miRNAs) are gene regulators involved in the pathogenesis of complex
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …
[HTML][HTML] The role of liquid biopsy in early diagnosis of lung cancer
C Freitas, C Sousa, F Machado, M Serino… - Frontiers in …, 2021 - frontiersin.org
Liquid biopsy is an emerging technology with a potential role in the screening and early
detection of lung cancer. Several liquid biopsy-derived biomarkers have been identified and …
detection of lung cancer. Several liquid biopsy-derived biomarkers have been identified and …
The role of MiRNA in cancer: pathogenesis, diagnosis, and treatment
Cancer is also determined by the alterations of oncogenes and tumor suppressor genes.
These gene expressions can be regulated by microRNAs (miRNA). At this point, researchers …
These gene expressions can be regulated by microRNAs (miRNA). At this point, researchers …
Role of regulatory miRNAs of the PI3K/AKT/mTOR signaling in the pathogenesis of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the common malignant human tumors with high
morbidity worldwide. Aberrant activation of the oncogenic phosphoinositide 3‐kinase/protein …
morbidity worldwide. Aberrant activation of the oncogenic phosphoinositide 3‐kinase/protein …
[HTML][HTML] Plasma level of circular RNA hsa_circ_0000190 correlates with tumor progression and poor treatment response in advanced lung cancers
Lung cancer (LC) causes the majority of cancer-related deaths. Circular RNAs (circRNAs)
were reported to play roles in cancers by targeting pro-and anti-oncogenic miRNAs …
were reported to play roles in cancers by targeting pro-and anti-oncogenic miRNAs …
[HTML][HTML] Recent advances on high-efficiency of microRNAs in different types of lung cancer: a comprehensive review
MS Sadeghi, M Lotfi, N Soltani, E Farmani… - Cancer Cell …, 2023 - Springer
Carcinoma of the lung is among the most common types of cancer globally. Concerning its
histology, it is categorized as a non-small cell carcinoma (NSCLC) and a small cell cancer …
histology, it is categorized as a non-small cell carcinoma (NSCLC) and a small cell cancer …
Material-enhanced biosensors for cancer biomarkers detection
X Sun, M Zhang, L Xie, Q Ren, J Chang, W Jiang - Microchemical Journal, 2023 - Elsevier
Cancer is a leading cause of death worldwide, the early diagnosis of which decides the
patient's prognosis. The accurate sensing of tumor biomarkers is becoming one of the most …
patient's prognosis. The accurate sensing of tumor biomarkers is becoming one of the most …
Sensing biomarkers with plasmonics
N Cathcart, JIL Chen - Analytical chemistry, 2020 - ACS Publications
The detection of biomarkers is critical for enabling early disease diagnosis, monitoring the
progression, and tracking the effectiveness of therapeutic intervention. Plasmonic sensors …
progression, and tracking the effectiveness of therapeutic intervention. Plasmonic sensors …
[HTML][HTML] Identifying circulating miRNA biomarkers for early diagnosis and monitoring of lung cancer
Liquid biopsy refers to the sampling, screening, and detecting potential biomarkers in
unique liquid samples for clinical use. Lung cancer is one of the most highly frequent cancer …
unique liquid samples for clinical use. Lung cancer is one of the most highly frequent cancer …