[HTML][HTML] RNA-based therapeutics: from antisense oligonucleotides to miRNAs

S Bajan, G Hutvagner - Cells, 2020 - mdpi.com
The first therapeutic nucleic acid, a DNA oligonucleotide, was approved for clinical use in
1998. Twenty years later, in 2018, the first therapeutic RNA-based oligonucleotide was …

Updated review of advances in microRNAs and complex diseases: experimental results, databases, webservers and data fusion

L Huang, L Zhang, X Chen - Briefings in bioinformatics, 2022 - academic.oup.com
MicroRNAs (miRNAs) are gene regulators involved in the pathogenesis of complex
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …

[HTML][HTML] The role of liquid biopsy in early diagnosis of lung cancer

C Freitas, C Sousa, F Machado, M Serino… - Frontiers in …, 2021 - frontiersin.org
Liquid biopsy is an emerging technology with a potential role in the screening and early
detection of lung cancer. Several liquid biopsy-derived biomarkers have been identified and …

The role of MiRNA in cancer: pathogenesis, diagnosis, and treatment

E Uzuner, GT Ulu, SB Gürler, Y Baran - miRNomics: MicroRNA Biology …, 2022 - Springer
Cancer is also determined by the alterations of oncogenes and tumor suppressor genes.
These gene expressions can be regulated by microRNAs (miRNA). At this point, researchers …

Role of regulatory miRNAs of the PI3K/AKT/mTOR signaling in the pathogenesis of hepatocellular carcinoma

F Rahmani, A Ziaeemehr, S Shahidsales… - Journal of cellular …, 2020 - Wiley Online Library
Hepatocellular carcinoma (HCC) is one of the common malignant human tumors with high
morbidity worldwide. Aberrant activation of the oncogenic phosphoinositide 3‐kinase/protein …

[HTML][HTML] Plasma level of circular RNA hsa_circ_0000190 correlates with tumor progression and poor treatment response in advanced lung cancers

YH Luo, YP Yang, CS Chien, AA Yarmishyn, AA Ishola… - Cancers, 2020 - mdpi.com
Lung cancer (LC) causes the majority of cancer-related deaths. Circular RNAs (circRNAs)
were reported to play roles in cancers by targeting pro-and anti-oncogenic miRNAs …

[HTML][HTML] Recent advances on high-efficiency of microRNAs in different types of lung cancer: a comprehensive review

MS Sadeghi, M Lotfi, N Soltani, E Farmani… - Cancer Cell …, 2023 - Springer
Carcinoma of the lung is among the most common types of cancer globally. Concerning its
histology, it is categorized as a non-small cell carcinoma (NSCLC) and a small cell cancer …

Material-enhanced biosensors for cancer biomarkers detection

X Sun, M Zhang, L Xie, Q Ren, J Chang, W Jiang - Microchemical Journal, 2023 - Elsevier
Cancer is a leading cause of death worldwide, the early diagnosis of which decides the
patient's prognosis. The accurate sensing of tumor biomarkers is becoming one of the most …

Sensing biomarkers with plasmonics

N Cathcart, JIL Chen - Analytical chemistry, 2020 - ACS Publications
The detection of biomarkers is critical for enabling early disease diagnosis, monitoring the
progression, and tracking the effectiveness of therapeutic intervention. Plasmonic sensors …

[HTML][HTML] Identifying circulating miRNA biomarkers for early diagnosis and monitoring of lung cancer

YH Zhang, M Jin, JR Li, XY Kong - … Acta (BBA)-Molecular Basis of Disease, 2020 - Elsevier
Liquid biopsy refers to the sampling, screening, and detecting potential biomarkers in
unique liquid samples for clinical use. Lung cancer is one of the most highly frequent cancer …