[PDF][PDF] Artificial intelligence for proteomics and biomarker discovery
There is an avalanche of biomedical data generation and a parallel expansion in
computational capabilities to analyze and make sense of these data. Starting with genome …
computational capabilities to analyze and make sense of these data. Starting with genome …
Advances in data‐independent acquisition mass spectrometry towards comprehensive digital proteome landscape
RB Kitata, JC Yang, YJ Chen - Mass spectrometry reviews, 2023 - Wiley Online Library
The data‐independent acquisition mass spectrometry (DIA‐MS) has rapidly evolved as a
powerful alternative for highly reproducible proteome profiling with a unique strength of …
powerful alternative for highly reproducible proteome profiling with a unique strength of …
[PDF][PDF] Proteome profiling of cerebrospinal fluid reveals biomarker candidates for Parkinson's disease
Parkinson's disease (PD) is a growing burden worldwide, and there is no reliable biomarker
used in clinical routines to date. Cerebrospinal fluid (CSF) is routinely collected in patients …
used in clinical routines to date. Cerebrospinal fluid (CSF) is routinely collected in patients …
[PDF][PDF] Proteomic and metabolomic profiling of urine uncovers immune responses in patients with COVID-19
X Bi, W Liu, X Ding, S Liang, Y Zheng, X Zhu, S Quan… - Cell reports, 2022 - cell.com
The utility of the urinary proteome in infectious diseases remains unclear. Here, we analyzed
the proteome and metabolome of urine and serum samples from patients with COVID-19 …
the proteome and metabolome of urine and serum samples from patients with COVID-19 …
Mass spectrometry‐based high‐throughput proteomics and its role in biomedical studies and systems biology
There are multiple reasons why the next generation of biological and medical studies
require increasing numbers of samples. Biological systems are dynamic, and the effect of a …
require increasing numbers of samples. Biological systems are dynamic, and the effect of a …
High-throughput proteomics and AI for cancer biomarker discovery
Q Xiao, F Zhang, L Xu, L Yue, OL Kon, Y Zhu… - Advanced drug delivery …, 2021 - Elsevier
Biomarkers are assayed to assess biological and pathological status. Recent advances in
high-throughput proteomic technology provide opportunities for developing next generation …
high-throughput proteomic technology provide opportunities for developing next generation …
Perspective on the current state of the LRRK2 field
JM Taymans, M Fell, T Greenamyre, WD Hirst… - npj Parkinson's …, 2023 - nature.com
Almost 2 decades after linking LRRK2 to Parkinson's disease, a vibrant research field has
developed around the study of this gene and its protein product. Recent studies have begun …
developed around the study of this gene and its protein product. Recent studies have begun …
Proteomics of human biological fluids for biomarker discoveries: technical advances and recent applications
L Dayon, O Cominetti, M Affolter - Expert review of proteomics, 2022 - Taylor & Francis
Introduction Biological fluids are routine samples for diagnostic testing and monitoring.
Blood samples are typically measured because of their moderate invasive collection and …
Blood samples are typically measured because of their moderate invasive collection and …
Proteomic discovery of non-invasive biomarkers of localized prostate cancer using mass spectrometry
Prostate cancer is the second most frequently diagnosed non-skin cancer in men worldwide.
Patient outcomes are remarkably heterogeneous and the best existing clinical prognostic …
Patient outcomes are remarkably heterogeneous and the best existing clinical prognostic …
Advances in proteomic and metabolomic profiling of neurodegenerative diseases
Proteomics and metabolomics are two emerging fields that hold promise to shine light on the
molecular mechanisms causing neurodegenerative diseases. Research in this area may …
molecular mechanisms causing neurodegenerative diseases. Research in this area may …