Freedom to err: The expanding cellular functions of translesion DNA polymerases
I Paniagua, JJL Jacobs - Molecular Cell, 2023 - cell.com
Translesion synthesis (TLS) DNA polymerases were originally described as error-prone
enzymes involved in the bypass of DNA lesions. However, extensive research over the past …
enzymes involved in the bypass of DNA lesions. However, extensive research over the past …
[HTML][HTML] Mass spectrometry-based assays for assessing replicative bypass and repair of DNA alkylation in cells
J Li, Z Hu, D Liu, P Wang - RSC advances, 2023 - pubs.rsc.org
Endogenous metabolism and environmental exposure can give rise to DNA alkylation,
which can elicit deleterious biological consequences. In the search for reliable and …
which can elicit deleterious biological consequences. In the search for reliable and …
Replication Studies of Alkyl Phosphotriester Lesions in Human Cells
Alkyl phosphotriester (alkyl-PTE) lesions in DNA are shown to be poorly repaired; however,
little is known about how these lesions impact DNA replication in human cells. Here, we …
little is known about how these lesions impact DNA replication in human cells. Here, we …
[HTML][HTML] From Mutation and Repair to Therapeutics
As DNA research has developed, in this Special Issue of DNA, we aimed to explore recent
advancements, with an emphasis on the DNA damage-induced alteration of cellular …
advancements, with an emphasis on the DNA damage-induced alteration of cellular …